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Merck
CN

SML0123

Deflazacort

≥98% (HPLC)

别名:

(11β,16β)-21-(acetyloxy)-11-hydroxy-2′-methyl-5′H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 11β,21-dihydroxy-2′-methyl-5′βH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 2′-acetate, DL-458-IT, L-5458, azacort, oxazacort, pregna-1,4-diene-11β,21-diol-3,20-dione[17α,16α-d]-2′-methyloxazoline 21-acetate

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关于此项目

经验公式(希尔记法):
C25H31NO6
化学文摘社编号:
分子量:
441.52
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
238-483-7
MDL number:
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InChI key

FBHSPRKOSMHSIF-GRMWVWQJSA-N

InChI

1S/C25H31NO6/c1-13-26-25(20(30)12-31-14(2)27)21(32-13)10-18-17-6-5-15-9-16(28)7-8-23(15,3)22(17)19(29)11-24(18,25)4/h7-9,17-19,21-22,29H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22+,23-,24-,25+/m0/s1

SMILES string

CC(=O)OCC(=O)[C@@]12N=C(C)O[C@@H]1C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]23C

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

DMSO: ≥20 mg/mL

storage temp.

2-8°C

Quality Level

Gene Information

human ... NR3C1(2908)

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Biochem/physiol Actions

Deflazacort is an Anti-inflammatory glucocorticoid
Deflazacort is an anti-inflammatory and immunosuppressant glucocorticoid.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 16(4), 373-378 (2011-12-27)
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Corticosteroids can reduce the severity of scoliosis in Duchenne muscular dystrophy.
Anne M Connolly et al.
The Journal of bone and joint surgery. American volume, 95(12), e86-e86 (2013-06-21)
Maggie C Walter et al.
Orphanet journal of rare diseases, 8, 26-26 (2013-02-15)
Dysferlinopathies are autosomal recessive disorders caused by mutations in the dysferlin (DYSF) gene encoding the dysferlin protein. DYSF mutations lead to a wide range of muscular phenotypes, with the most prominent being Miyoshi myopathy (MM) and limb girdle muscular dystrophy

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