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经验公式(希尔记法):
C25H31NO6
化学文摘社编号:
分子量:
441.52
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
238-483-7
MDL number:
InChI key
FBHSPRKOSMHSIF-GRMWVWQJSA-N
InChI
1S/C25H31NO6/c1-13-26-25(20(30)12-31-14(2)27)21(32-13)10-18-17-6-5-15-9-16(28)7-8-23(15,3)22(17)19(29)11-24(18,25)4/h7-9,17-19,21-22,29H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22+,23-,24-,25+/m0/s1
SMILES string
CC(=O)OCC(=O)[C@@]12N=C(C)O[C@@H]1C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]23C
assay
≥98% (HPLC)
form
powder
color
white to tan
solubility
DMSO: ≥20 mg/mL
storage temp.
2-8°C
Quality Level
Gene Information
human ... NR3C1(2908)
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Biochem/physiol Actions
Deflazacort is an Anti-inflammatory glucocorticoid
Deflazacort is an anti-inflammatory and immunosuppressant glucocorticoid.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
David E Lebel et al.
The Journal of bone and joint surgery. American volume, 95(12), 1057-1061 (2013-06-21)
Duchenne muscular dystrophy, a progressive muscle disorder that occurs in males, causes a gradual decline in muscle strength. This progressive decline is associated with the development of scoliosis. Previous studies have shown that the use of glucocorticoids slows the progression
Siliconosis: autoimmune/inflammatory syndrome induced by adjuvants (ASIA).
Mónica Caldeira et al.
The Israel Medical Association journal : IMAJ, 14(2), 137-138 (2012-06-15)
Acute and chronic corticosteroid treatment of ten patients with paralytic form of Sydenham's chorea.
Carlo Fusco et al.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 16(4), 373-378 (2011-12-27)
To determine efficacy and safety of corticosteroid treatment in patients with severe Sydenham's chorea paralytic form. This is a 4 years observational study on ten patient with severe paralytic form of Sydenham's chorea unresponsive to neuroleptics and antiepileptics agents, treated
Corticosteroids can reduce the severity of scoliosis in Duchenne muscular dystrophy.
Anne M Connolly et al.
The Journal of bone and joint surgery. American volume, 95(12), e86-e86 (2013-06-21)
Maggie C Walter et al.
Orphanet journal of rare diseases, 8, 26-26 (2013-02-15)
Dysferlinopathies are autosomal recessive disorders caused by mutations in the dysferlin (DYSF) gene encoding the dysferlin protein. DYSF mutations lead to a wide range of muscular phenotypes, with the most prominent being Miyoshi myopathy (MM) and limb girdle muscular dystrophy
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