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Merck
CN

SML0153

栀子苷

≥98% (HPLC), iridoid glycoside, powder

别名:

(1S,4αS,7αS) -1-(β-D-吡喃葡萄糖氧基)-1,4a,5,7a-四氢-7-(羟甲基)-环戊[c]吡喃 -4-羧酸甲酯

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关于此项目

经验公式(希尔记法):
C17H24O10
化学文摘社编号:
分子量:
388.37
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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产品名称

栀子苷, ≥98% (HPLC)

质量水平

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to beige

溶解性

H2O: ≥5 mg/mL

运输

wet ice

储存温度

−20°C

SMILES字符串

COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1CC=C3CO

InChI

1S/C17H24O10/c1-24-15(23)9-6-25-16(11-7(4-18)2-3-8(9)11)27-17-14(22)13(21)12(20)10(5-19)26-17/h2,6,8,10-14,16-22H,3-5H2,1H3/t8-,10-,11-,12-,13+,14-,16+,17+/m1/s1

InChI key

IBFYXTRXDNAPMM-BVTMAQQCSA-N

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生化/生理作用

栀子苷是一种具有抗氧化和其他生物活性的环烯醚萜苷。
栀子苷是一种环烯醚萜苷,具有多种生物活性,包括神经保护、抗糖尿病、抗增殖和抗氧化活性。研究表明,栀子苷可调节 Nrf2 转运,并通过 PI3K/Akt 信号通路上调下游抗氧化蛋白 HO-1 的表达,这可能是其神经保护和抗氧化活性的机制。胰高血糖素样肽 1(GLP-1)受体也可能在栀子苷诱导的 HO-1 表达中起关键作用。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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