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经验公式(希尔记法):
C17H24O10
化学文摘社编号:
分子量:
388.37
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
产品名称
栀子苷, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: ≥5 mg/mL
运输
wet ice
储存温度
−20°C
SMILES字符串
COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]3[C@@H]1CC=C3CO
InChI
1S/C17H24O10/c1-24-15(23)9-6-25-16(11-7(4-18)2-3-8(9)11)27-17-14(22)13(21)12(20)10(5-19)26-17/h2,6,8,10-14,16-22H,3-5H2,1H3/t8-,10-,11-,12-,13+,14-,16+,17+/m1/s1
InChI key
IBFYXTRXDNAPMM-BVTMAQQCSA-N
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生化/生理作用
栀子苷是一种具有抗氧化和其他生物活性的环烯醚萜苷。
栀子苷是一种环烯醚萜苷,具有多种生物活性,包括神经保护、抗糖尿病、抗增殖和抗氧化活性。研究表明,栀子苷可调节 Nrf2 转运,并通过 PI3K/Akt 信号通路上调下游抗氧化蛋白 HO-1 的表达,这可能是其神经保护和抗氧化活性的机制。胰高血糖素样肽 1(GLP-1)受体也可能在栀子苷诱导的 HO-1 表达中起关键作用。
警示用语:
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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