SML0494
VU0361737
≥98% (HPLC)
别名:
CID-44191096, ML128, N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C13H11ClN2O2
化学文摘社编号:
分子量:
262.69
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
film
Quality Segment
assay
≥98% (HPLC)
form
film
color
white
solubility
DMSO: 15 mg/mL (clear solution)
storage temp.
2-8°C
SMILES string
COc1cc(NC(=O)c2ccccn2)ccc1Cl
InChI
1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
InChI key
ARYUXFNGXHNNDM-UHFFFAOYSA-N
Biochem/physiol Actions
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM).
Features and Benefits
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable