SML1526
依托哌嗪(Eltoprazine) 盐酸盐
≥98% (HPLC)
别名:
1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride
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关于此项目
经验公式（希尔记法）:
C12H16N2O2 · HCl
化学文摘社编号:
分子量:
256.73
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
产品名称
依托哌嗪(Eltoprazine) 盐酸盐, ≥98% (HPLC)
InChI key
JFSOSUNPIXJCIX-UHFFFAOYSA-N
SMILES string
[H]Cl.C1(OCCO2)=C2C(N3CCNCC3)=CC=C1
InChI
1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: 10 mg/mL, clear
storage temp.
room temp
Quality Level
相关类别
Biochem/physiol Actions
Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. It has Ki values for 5-HT1A, 5-HT1B and 5-HT1C receptors of 40 nM and 52 nM, respectively.
Serotonin 5-HT1A/1B receptor agonist
General description
Eltoprazine, a serotonergic agent, possesses specific anti-aggressive (serenic) properties in various animal models without triggering sedation, motor disturbances, or muscle relaxation.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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