SML2173
NS3861
≥98% (HPLC)
别名:
3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene, NS 3861
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Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
BrC1=C(SC=C1)C2=CC(N3C)CCC3C2
InChI key
ZJCNRVHZJADROC-UHFFFAOYSA-N
Biochem/physiol Actions
α3β2 heteromeric neuronal nAChRs agonist
NS3861 is a neuronal nicotinic receptor agonist that selectively activates α3 containing nAChRs and it displays higher efficacy at the α3β2 receptor compared with the α3β4 receptor. NS3861 does not activate α4 containing receptors. NS3861 was reported to reverse chronic opioid-induced constipation in vivo.
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable