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Merck
CN

SML2173

NS3861

≥98% (HPLC)

别名:

3-(3-Bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene, NS 3861

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关于此项目

经验公式(希尔记法):
C12H14BrNS
化学文摘社编号:
分子量:
284.22
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

BrC1=C(SC=C1)C2=CC(N3C)CCC3C2

InChI key

ZJCNRVHZJADROC-UHFFFAOYSA-N

Biochem/physiol Actions

α3β2 heteromeric neuronal nAChRs agonist
NS3861 is a neuronal nicotinic receptor agonist that selectively activates α3 containing nAChRs and it displays higher efficacy at the α3β2 receptor compared with the α3β4 receptor. NS3861 does not activate α4 containing receptors. NS3861 was reported to reverse chronic opioid-induced constipation in vivo.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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