SML2313
Higenamine hydrochloride
≥95% (HPLC)
别名:
Higenamine hydrochloride, (RS)-Norcoclaurine hydrochloride, (±)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-Isoquinolinediol hydrochloride, (±)-Demethylcoclaurine, (±)-Norcoclaurine hydrochloride, (±)-O-Demethylcoclaurine hydrochloride, 1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-isoquinolinediol hydrochloride, dl-Demethylcoclaurine hydrochloride, (±)-Demethylcoclaurine hydrochloride
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关于此项目
经验公式（希尔记法）:
C16H17NO3 · HCl
化学文摘社编号:
分子量:
307.77
UNSPSC Code:
12352116
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
OC1=C(O)C=C(C(CC2=CC=C(O)C=C2)NCC3)C3=C1.Cl
InChI
1S/C16H17NO3.ClH/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14;/h1-4,8-9,14,17-20H,5-7H2;1H
InChI key
SWWQQSDRUYSMAR-UHFFFAOYSA-N
Biochem/physiol Actions
Higenamine is an anti-inflammatory agent that protects cells from oxidant injury. Higenamine is a pharmacological modulator of heme oxygenase 1(HO-1). It also displays agonist activity at adrenergic β2 receptor.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Wenjiang Duan et al.
Experimental and therapeutic medicine, 12(5), 3107-3112 (2016-11-25)
Existing in Ranunculaceae Aconitum and tomato, with the chemical name 1-phydroxybenzyl-1,2,3,4-tetrahy-droisoquinoline, higenamine is widely distributed in China. Higenamine's anti-inflammatory, antioxidant and anti-apoptotic effects have been identified in previous studies. The present study attempted to determine the protective effect of higenamine
Xiaoxia An et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 95, 1710-1717 (2017-09-30)
Diabetic gastroparesis (DGP) is a common complication of diabetes mellitus (DM). The numerous clinical symptoms of DGP and the great cost on the treatment of DGP seriously lowered the patients' life quality. However, the pathogenic mechanism of DGP is still
Eisuke Kato et al.
Bioorganic & medicinal chemistry, 25(24), 6412-6416 (2017-10-27)
β2-Adrenergic receptor (β2AR) agonists are employed as bronchodilators to treat pulmonary disorders, but are attracting attention for their modulation of glucose handling and energy expenditure. Higenamine is a tetrahydroisoquinoline present in several plant species and has β2AR agonist activity, but
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML2313-25MG | 04061838693389 |
| SML2313-5MG | 04061838693501 |