SML3348
JWH-018
≥98% (HPLC)
别名:
1-Naphthalenyl(1-pentyl-1H-indol-3-yl)methanone, 3-(1-Naphthoyl)-1-pentylindole, AM 678, JWH 018
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关于此项目
经验公式（希尔记法）:
C24H23NO
化学文摘社编号:
分子量:
341.45
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
InChI
1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3
SMILES string
O=C(C1=CN(CCCCC)C2=C1C=CC=C2)C3=CC=CC4=C3C=CC=C4
InChI key
JDNLPKCAXICMBW-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
Quality Level
drug control
USDEA Schedule I; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
JWH-018, a synthetic cannabinoid, is a potent and selective full agonist at the CB1 and CB2 cannabinoid receptors. JWH-018 mimic the effects of Δ9-tetrahydrocannabinol (THC) and is found in several versions of the herbal mixture “Spice.”
Potent and selective full agonist at the CB1 and CB2 cannabinoid receptors
Legal Information
German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.
English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.
English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
signalword
Warning
hcodes
Hazard Classifications
STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Cross-substitution of ?9-tetrahydrocannabinol and JWH-018 in drug discrimination in rats
Jenny L Wiley
Pharmacology, Biochemistry, and Behavior, 124, 123-128 (2014)
JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist
Brady K Atwood
British Journal of Pharmacology, 160, 585-593 (2010)
Synthetic cannabinoids JWH-018, JWH-122, UR-144 and the phytocannabinoid THC activate apoptosis in placental cells
Marta Almada, Patricia Alves, Bruno M Fonseca, Cristina Amaral , Natercia A Teixeira
Toxicology Letters, 319, 129-137 (2020)
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