质量水平
方案
≥98% (HPLC)
表单
solid
储存条件
desiccated
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
NCCC1=CC=C(C2=CC(F)=CC=C2)C=C1.Cl
InChI key
UFFLABDFGANWCU-UHFFFAOYSA-N
相关类别
生化/生理作用
orally available, potent and selective activator of Trace amine-associated receptor 1 (TAAR1); only activates Gs in mTAAR1/hTAAR1-overexpressing cells.
ZH8667 is an orally available, potent and selective activator of Trace amine-associated receptor 1 (TAAR1). ZH8667 only activates Gs in mTAAR1/hTAAR1-overexpressing cells (EC50 = 1.17 nM (Gs).
ZH8667 is an orally available, potent and selective activator of Trace amine-associated receptor 1 (TAAR1). ZH8667 only activates Gs in mTAAR1/hTAAR1-overexpressing cells (EC50 = 1.17 nM (Gs).
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Pan Shang et al.
Cell, 186(24), 5347-5362 (2023-11-15)
Trace amine-associated receptor 1 (TAAR1) senses a spectrum of endogenous amine-containing metabolites (EAMs) to mediate diverse psychological functions and is useful for schizophrenia treatment without the side effects of catalepsy. Here, we systematically profiled the signaling properties of TAAR1 activation
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