产品名称
抗-肿瘤坏死因子-α 山羊抗, affinity isolated antibody, lyophilized powder
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
mouse
technique(s)
capture ELISA: suitable
flow cytometry: 5-25 μg/mL
indirect immunofluorescence: 15 μg/mL using mouse cells and tissues
neutralization: suitable
western blot: 0.1-0.2 μg/mL
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Tnf(21926)
正在寻找类似产品? 访问 产品对比指南
Application
抗肿瘤坏死因子α抗体可用于ELISA捕获和流式细胞术。它还可用于免疫印迹法。
Biochem/physiol Actions
该抗体中和重组小鼠TNF-α的生物学活性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
肿瘤坏死因子-α（TNF-α）是由脂多糖刺激的巨噬细胞产生的蛋白质，可引起肿瘤坏死。它还促进许多功能，例如刺激人成纤维细胞和其他细胞系的生长，激活多形核中性粒细胞和破骨细胞以及胶原酶的产生。抗肿瘤坏死因子α抗体可用于中和重组小鼠TNF-α的生物学活性。也可用于间接免疫荧光。山羊抗肿瘤坏死因子α抗体与重组小鼠TNF-α特异性反应。
Immunogen
重组小鼠TNF-α
Physical form
从含有5％海藻糖的磷酸盐缓冲生理盐水的0.2 μm过滤的溶液中冻干。
Preparation Note
使用小鼠TNF-α亲和层析进行纯化。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
E A Carswell et al.
Proceedings of the National Academy of Sciences of the United States of America, 72(9), 3666-3670 (1975-09-01)
In studying "hemorrhagic necrosis" of tumors produced by endotoxin, it was found that the serum of bacillus Calmette--Guerin (BCG)-infected mice treated with endotoxin contains a substance (tumor necrosis factor; TNF) which mimics the tumor necrotic action of endotoxin itself. TNF-positive
D R Bertolini et al.
Nature, 319(6053), 516-518 (1986-02-06)
When leukocytes are exposed to mitogens or antigens in vitro, they release bone-resorbing activity into the culture supernatants which can be detected by bioassay. Like many lymphocyte-monocyte products, this activity has been difficult to purify because of its low abundance
Jih-Hua Wei et al.
International journal of molecular sciences, 24(6) (2023-03-30)
Bariatric surgery reduces body weight, enhances metabolic and diabetic control, and improves outcomes on obesity-related comorbidities. However, the mechanisms mediating this protection against cardiovascular diseases remain unclear. We investigated the effect of sleeve gastrectomy (SG) on vascular protection in response
J M Dayer et al.
The Journal of experimental medicine, 162(6), 2163-2168 (1985-12-01)
Cachectin/TNF (tumor necrosis factor), an endotoxin-induced murine macrophage hormone implicated in the pathogenesis of cachexia and shock, has been found capable of stimulating collagenase and prostaglandin E2 (PGE2) production by isolated human synovial cells and dermal fibroblasts. This bioactivity associated
B J Sugarman et al.
Science (New York, N.Y.), 230(4728), 943-945 (1985-11-22)
Modulation of the growth of human and murine cell lines in vitro by recombinant human tumor necrosis factor-alpha (rTNF-alpha) and recombinant human interferon-gamma (rIFN-gamma) was investigated. rTNF-alpha had cytostatic or cytolytic effects on only some tumor cell lines. When administered
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持