T0951
抗四环素阻遏蛋白（TETR） 兔抗
affinity isolated antibody, buffered aqueous solution
别名:
抗四环素阻遏蛋白
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
5
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~22 kDa by calculation
species reactivity
human
technique(s)
indirect ELISA: suitable, western blot: 1:1,000
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
General description
四环素阻遏蛋白 (TETR) 是一种同源二聚体，含C端螺旋―转角―螺旋 (HTH) 和N端DNA结合结构域。C端还含四环素结合和二聚化 (TBD) 结构域。
Immunogen
Tet阻遏蛋白（TETR）与22 kDa Tet阻遏蛋白的氨基酸残基 31-49 (AQKLGVEQPTLYWHVKNKR) 反应
Application
兔源四环素阻遏蛋白 (TETR) 抗体可用于蛋白印迹分析。
Biochem/physiol Actions
四环素系统可用于研究真核细胞条件性基因表达系统。对于某些生物，TetR无需进一步的修饰即可用于这类应用。但对于哺乳动物和其他多种生物，TetR需要融合真核转录激活或阻遏因子才能成为有效的调控因子。TetR可与四环素抗生素作用，降低其与DNA的结合亲和力。
Physical form
溶剂为含有0.02％叠氮化钠的1 mg/mL磷酸盐缓冲盐水。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
常规特殊物品
此项目有
The TetR family of transcriptional repressors
Ramos JL, et al.
Microbiology and Molecular Biology Reviews, 69(2), 326-356 (2005)
The induction of folding cooperativity by ligand binding drives the allosteric response of tetracycline repressor
Reichheld SE, et al.
Proceedings of the National Academy of Sciences of the USA, 106(52), 22263-22268 (2009)
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
Zhang X, et al.
Nature Cell Biology, 13(9), 1092-1092 (2011)
The application of Tet repressor in prokaryotic gene regulation and expression
Bertram R and Hillen W
Microbial Biotechnology, 1(1), 2-16 (2008)
Alicia Broto et al.
Nature communications, 13(1), 1910-1910 (2022-04-09)
Mycoplasmas have exceptionally streamlined genomes and are strongly adapted to their many hosts, which provide them with essential nutrients. Owing to their relative genomic simplicity, Mycoplasmas have been used to develop chassis for biotechnological applications. However, the dearth of robust
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