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Merck
CN

T1694

(E)-4-Amino-2-butenoic acid

别名:

trans-4-Aminocrotonic acid, TACA

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关于此项目

经验公式(希尔记法):
C4H7NO2
化学文摘社编号:
分子量:
101.10
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Form:
powder
Quality level:
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InChI

1S/C4H7NO2/c5-3-1-2-4(6)7/h1-2H,3,5H2,(H,6,7)/b2-1+

SMILES string

NC\C=C\C(O)=O

InChI key

FMKJUUQOYOHLTF-OWOJBTEDSA-N

form

powder

color

white

solubility

H2O: 10 mg/mL, clear

Quality Level

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Kinga K Borowicz et al.
Pharmacological reports : PR, 57(1), 121-123 (2005-04-26)
In the present study, we evaluated TACA (a potent agonist of GABA(A) and GABA(C) receptors) in the electroconvulsive threshold test in mice. Surprisingly, TACA (at 15 and 25 mg/kg) significantly decreased the threshold. The highest ineffective dose of TACA was
D Zhang et al.
Trends in pharmacological sciences, 22(3), 121-132 (2001-03-10)
In less than a decade our knowledge of the GABA(C) receptor, a new type of Cl(-)-permeable ionotropic GABA receptor, has greatly increased based on studies of both native and recombinant receptors. Careful comparison of properties of native and recombinant receptors
M Kurjak et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 23(5), e181-e190 (2011-03-19)
γ-Aminobutyric acid (GABA) acts on specific neural receptors [A, B and C(Aρ)] to modulate gastrointestinal function. The precise role of GABA receptor activation in the regulation of presynaptic nitric oxide (NO) synthesis in nerve terminals is unknown. Rat ileal nerve
Seung Yun Yang et al.
Nature communications, 4, 1702-1702 (2013-04-18)
Achieving significant adhesion to soft tissues while minimizing tissue damage poses a considerable clinical challenge. Chemical-based adhesives require tissue-specific reactive chemistry, typically inducing a significant inflammatory response. Staples are fraught with limitations including high-localized tissue stress and increased risk of
Ralph J Jensen
PloS one, 8(10), e79126-e79126 (2013-11-10)
Retinitis pigmentosa (RP) is a progressive retinal degenerative disease that causes deterioration of rod and cone photoreceptors. A well-studied animal model of RP is the transgenic P23H rat, which carries a mutation in the rhodopsin gene. Previously, I reported that

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