T7665
Tyrphostin 51
≥98%
别名:
2-Amino-1,1,3-tricyano-4-(3′,4′,5′-trihydroxyphenyl)butadiene
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C13H8N4O3
化学文摘社编号:
分子量:
268.23
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98%
Form:
powder
biological source
synthetic (organic)
Quality Segment
assay
≥98%
form
powder
potency
0.8 μM IC50
solubility
DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red
storage temp.
2-8°C
SMILES string
NC(\C(=C\c1cc(O)c(O)c(O)c1)C#N)=C(/C#N)C#N
InChI
1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+
InChI key
JKNOYWVMHPMBEL-UNXLUWIOSA-N
Gene Information
human ... CDK2(1017), EGFR(1956)
Application
Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1.
Biochem/physiol Actions
EGFR tyrosine kinase inhibitor.
Tyrphostin 51 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Preparation Note
5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
Discover Bioactive Small Molecules for Kinase Phosphatase Biology
相关内容
Product Information Sheet
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T7665-5MG | 04061837378539 |
| T7665-25MG | 04061832964263 |