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About This Item
经验公式（希尔记法）:
C13H8N4O3
CAS Number:
分子量:
268.23
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
生物来源
synthetic (organic)
质量水平
方案
≥98%
表单
powder
效能
0.8 μM IC50
溶解性
DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red
储存温度
2-8°C
SMILES字符串
NC(\C(=C\c1cc(O)c(O)c(O)c1)C#N)=C(/C#N)C#N
InChI
1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+
InChI key
JKNOYWVMHPMBEL-UNXLUWIOSA-N
基因信息
human ... CDK2(1017), EGFR(1956)
应用
Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1.
生化/生理作用
EGFR tyrosine kinase inhibitor.
Tyrphostin 51 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
特点和优势
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制备说明
5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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