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Merck
CN

U6625

Sigma-Aldrich

尿苷-5′-三磷酸酯 三钠盐 水合物

From yeast, ≥96%, P2Y receptor agonist

别名:

UTP Na3

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关于此项目

经验公式(希尔记法):
C9H12N2Na3O15P3 · xH2O
化学文摘社编号:
分子量:
550.09 (anhydrous basis)
Beilstein:
3585234
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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产品名称

尿苷-5′-三磷酸酯 三钠盐 水合物, from yeast, Type III, ≥96%

生物来源

yeast

质量水平

类型

Type III

方案

≥96%

溶解性

H2O: soluble 50 mg/mL, clear to slightly hazy, colorless

运输

dry ice

储存温度

−20°C

SMILES字符串

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

InChI key

MMJGIWFJVDOPJF-LLWADOMFSA-K

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应用

UTP已用于研究其对糖尿病患者的骨骼肌细胞的血管舒张作用。UTP 还被用作嘌呤能激动剂来研究 P2Y2 受体在大鼠基底外侧膜上的离子转运功能

生化/生理作用

P2Y 受体激动剂。

制备说明

尿苷 5′-三磷酸三钠盐(UTP Na3)水合物,以 50mg/ml的浓度溶于水,产生澄清至轻微浑浊的无色溶液。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xiping Chen et al.
FEBS letters, 595(1), 110-122 (2020-10-25)
O-GlcNAcylation is a post-translational modification catalysed by O-GlcNAc transferase (OGT). Missense mutations in OGT have been associated with developmental disorders, OGT-linked congenital disorder of glycosylation (OGT-CDG), which are characterized by intellectual disability. OGT relies on the hexosamine biosynthetic pathway (HBP)
Satyanarayana R Pondugula et al.
BMC research notes, 3, 100-100 (2010-04-20)
The ionic composition of the luminal fluid in the vestibular labyrinth is maintained within tight limits by the many types of epithelial cells bounding the lumen. Regulatory mechanisms include systemic, paracrine and autocrine hormones along with their associated intracellular signal
Alexander Puzenko et al.
The Journal of chemical physics, 137(19), 194502-194502 (2012-11-28)
In this, the third part of our series on the dielectric spectrum symmetrical broadening of water, we consider the nucleotide aqueous solutions. Where in Parts I [E. Levy et al., J. Chem. Phys. 136, 114502 (2012)] and II [E. Levy
Adelaine K W Leung et al.
Journal of molecular biology, 402(1), 154-164 (2010-07-21)
RNA is known to perform diverse roles in the cell, often as ribonucleoprotein (RNP) particles. While the crystal structure of these RNP particles could provide crucial insights into their functions, crystallographic work on RNP complexes is often hampered by difficulties
Kazuyuki Takai et al.
Nature protocols, 5(2), 227-238 (2010-02-06)
Biochemical characterization of each gene product encoded in the genome is essential to understand how cells are regulated. The bottleneck has been and still is in how the gene products can be obtained. The wheat cell-free protein synthesis system we

实验方案

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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