WH0255631M7
Monoclonal Anti-COL24A1 antibody produced in mouse
clone 1D8, purified immunoglobulin, buffered aqueous solution
别名:
Anti-collagen, type XXIV, alpha 1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1D8, monoclonal
Application:
ELISA (i), WB
Citations:
2
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1D8, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: suitable, western blot: 1-5 μg/mL
isotype
IgG2aκ
GenBank accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... COL24A1(255631)
General description
Collagen type XXIV α 1 (COL24A1) is part of the fibril-forming family of collagen molecules and is expressed in bones.
Immunogen
COL24A1 (NP_690850, 1626 a.a. ~ 1714 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL
Sequence
PRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL
Biochem/physiol Actions
Collagen type XXIV α 1 (COL24A1) takes part in modulating various processes in the cartilage and bone. It has been linked to head and neck squamous cell carcinoma.
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
CREB-AP1 protein complexes regulate transcription of the collagen XXIV gene (Col24a1) in osteoblasts.
Matsuo N
The Journal of Biological Chemistry, 281(9), 5445-5452 (2006)
Kiyoshi Misawa et al.
Molecular and clinical oncology, 2(2), 285-291 (2014-03-22)
Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most common type of cancer, affecting ~500,000 individuals worldwide annually. Collagen is the major constituent of the extracellular matrix component in tumors and plays a crucial role in
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