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Merck
CN

Z4402

Sigma-Aldrich

Zinterol hydrochloride

≥98% (HPLC)

别名:

Zinterol hydrochloride, N-[5-[2-[(1,1-dimethyl-2-phenylethyl)amino]-1-hydroxyethyl]-2-hydroxyphenyl]-Methanesulfonamide Hydrochloride; MJ 9184

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关于此项目

经验公式（希尔记法）:
C19H26N2O4S·HCl
化学文摘社编号:
38241-28-0
分子量:
414.95
MDL编号:
MFCD00867031
UNSPSC代码:
12352200
PubChem化学物质编号:
329831614
NACRES:
NA.77

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质量水平

100

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

溶解性

DMSO: ≥15 mg/mL

储存温度

room temp

SMILES字符串

CC(C)(Cc1ccccc1)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2

InChI

1S/C19H26N2O4S/c1-19(2,12-14-7-5-4-6-8-14)20-13-18(23)15-9-10-17(22)16(11-15)21-26(3,24)25/h4-11,18,20-23H,12-13H2,1-3H3

InChI key

XJBCFFLVLOPYBV-UHFFFAOYSA-N

相关类别

生化/生理作用

Zinterol Hydrochloride is a β2 adrenergic receptor selective agonist.

特点和优势

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H319

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
051M4733V
0000041742
0000041741

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Trevor W R Lee et al.
Anesthesiology, 98(2), 499-510 (2003-01-29)
This double-blind, randomized, controlled trial examined the effect of high-dose intrathecal bupivacaine in combination with general anesthesia on atrial beta-adrenergic receptor function, the stress response, and hemodynamics during coronary artery bypass graft surgery. Thirty-eight patients were randomized to either control
Bouziane Ait-Mamar et al.
The Journal of biological chemistry, 280(19), 18881-18890 (2005-02-25)
We have recently demonstrated that in human heart, beta2-adrenergic receptors (beta2-ARs) are biochemically coupled not only to the classical adenylyl cyclase (AC) pathway but also to the cytosolic phospholipase A2 (cPLA2) pathway (Pavoine, C., Behforouz, N., Gauthier, C., Le Gouvello
Ismayil Ahmet et al.
Circulation, 110(9), 1083-1090 (2004-08-18)
Studies in isolated cardiac myocytes have demonstrated that signaling via specific beta1-adrenergic receptor subtypes (beta1ARs) promotes but that signaling via beta2ARs protects from cell death. We hypothesized that prolonged beta(2)AR stimulation or beta1AR blockade would each protect myocytes from death
H E Lara et al.
Endocrine, 15(2), 187-192 (2001-11-27)
We investigated the possibility that norepinephrine from the human ovary is released after nerve stimulation and that this neurotransmitter is coupled to a steroidogenic response. Biologically significant levels of both norepinephrine and dopamine were found in human ovarian biopsies. [3H]norepinephrine
Su-Hyun Jo et al.
Circulation research, 91(1), 46-53 (2002-07-13)
Compartmentation of intracellular signaling pathways serves as an important mechanism conferring the specificity of G protein-coupled receptor (GPCR) signaling. In the heart, stimulation of beta2-adrenoceptor (beta2-AR), a prototypical GPCR, activates a tightly localized protein kinase A (PKA) signaling, which regulates
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