Z4751
Anti-Zyxin antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
别名:
Anti-ESP-2, Anti-HED-2
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, WB CL
Citations:
11
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 82-84 kDa
species reactivity
mouse, human, rat
technique(s)
indirect immunofluorescence: 1:100 using Rat1 cells, western blot (chemiluminescent): 1:1,000 using whole extract of human HeLa cells, western blot (chemiluminescent): 1:2,000 using whole extract of mouse NIH3T3 cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ZYX(7791)
mouse ... Zyx(22793)
rat ... Zyx(114636)
General description
Zyxin (ZYX ), a zinc-binding phosphoprotein of ∼61kDa is located at focal adhesions and along the actin cytoskeleton. It has three LIM domains. This structural protein is located on human chromosome 7q34.
Immunogen
synthetic peptide corresponding to amino acid residues 134-150 of human zyxin with N-terminal added cysteine conjugated to KLH. The corresponding sequence differs by one amino acid in mouse.
Application
Anti-Zyxin antibody has been used in fluorescence microscopy.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 papers)
Western Blotting (1 papers)
Biochem/physiol Actions
Zyxin (ZYX ) participates in the modulation of actin assembly at focal adhesions and stress fibers. It also regulates cell adhesion and cell cycle. Overexpression of ZYX is associated with melanoma. Suppression of ZYX prevents cell growth.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Loss of the mechanotransducer zyxin promotes a synthetic phenotype of vascular smooth muscle cells
Ghosh SK, et al.
Journal of the American Heart Association, 4(6), e001712-e001712 (2015)
Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells Corrigendum in/10.3892/ijo. 2016.3702
Yamamura MN, et al.
International Journal of Oncology, 42(3), 873-880 (2013)
Novel identification of zyxin upregulations in the motile phenotype of hepatocellular carcinoma
Sy SMH, et al.
Modern Pathology, 19(8), 1108-1108 (2006)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| Z4751-200UL | 04061837877643 |