442685
N-亚硝基-n-丁胺
analytical standard
别名:
N-亚硝基二丁胺, NDBA, 二丁基亚硝胺
等级
analytical standard
CofA
current certificate can be downloaded
包装
ampule of 100 mg
制造商/商品名称
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
技术
HPLC: suitable
gas chromatography (GC): suitable
密度
0.9 g/mL (lit.)
应用
environmental
包装形式
neat
储存温度
2-30°C
SMILES字符串
CCCCN(CCCC)N=O
InChI
1S/C8H18N2O/c1-3-5-7-10(9-11)8-6-4-2/h3-8H2,1-2H3
InChI key
YGJHZCLPZAZIHH-UHFFFAOYSA-N
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一般描述
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodi-n-butylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosodi-n-butylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
应用
NDBA可用作固相萃取（SPE）与气相色谱-三重四极杆质谱联用测定水中分析物和SPE与气相色谱-氮化学发光检测法（GC-NCD）联用测定肉制品中分析物的参考标准品 。它可用作液相色谱-串联质谱（SPE-LC-MS）法分析经反渗透以及SPE和紫外处理后的废水中残留NDBA的参考标准品。
分析说明
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 2
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
A robust analytical method for simultaneous quantification of 13 low-molecular-weight N-Nitrosamines in various pharmaceuticals based on solid phase extraction and liquid chromatography coupled to high-resolution mass spectrometry
Parfant T, et al.
European Journal of Pharmaceutical Sciences, 192, 106633-106633 (2024)
N-nitrosodimethylamine (NDMA) removal by reverse osmosis and UV treatment and analysis via LC -MS/MS
Plumlee MH, et al.
Water Research, 42(1-2), 347 -3355 (2008)
A new method for quantifying N-nitrosamines in wastewater samples by gas chromatography?triple quadrupole mass spectrometry
Yoon S, et al.
Talanta, 97, 256 -2261 (2012)
Analysis of N-nitrosamines in water by isotope dilution gas chromatography -electron ionisation tandem mass spectrometry
McDonald JA, et al.
Talanta, 99, 146 -1154 (2012)
Determination of volatile nitrosamines in various meat products using comprehensive gas chromatography -nitrogen chemiluminescence detection
Ozel MZ, et al.
Food And Chemical Toxicology, 48(11), 3268 -33273 (2010)
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