等级
analytical standard
CofA
current certificate can be downloaded
包装
ampule of 100 mg
制造商/商品名称
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
cleaning products
cosmetics
environmental
food and beverages
personal care
包装形式
neat
储存温度
2-30°C
SMILES字符串
CCCN(CCC)N=O
InChI
1S/C6H14N2O/c1-3-5-8(7-9)6-4-2/h3-6H2,1-2H3
InChI key
YLKFDHTUAUWZPQ-UHFFFAOYSA-N
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一般描述
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodi-n-propylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosodi-n-propylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
应用
N-亚硝基二正-丙基胺可用作分析参考标准品，用于通过气相色谱-三重四极杆质谱测定废水样品中的分析物。
分析说明
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Development and validation of GC-FID method for the determination of volatile N-nitrosamines in meat
Al-Kaseem M, et al.
International Journal of Pharmaceutical Sciences Review and Research, 25, 59-64 (2014)
A new method for quantifying N-nitrosamines in wastewater samples by gas chromatography?triple quadrupole mass spectrometry.
Yoon S, et al.
Talanta, 97, 256-261 (2012)
A Martelli et al.
Cancer research, 48(15), 4144-4152 (1988-08-01)
Ten carcinogenic N-nitroso compounds were assayed for DNA-damaging activity in primary cultures of human and rat hepatocytes. DNA fragmentation was measured by the alkaline elution technique, and unscheduled DNA synthesis by quantitative autoradiography. Positive dose-related responses in the range of
S M Billedeau et al.
Journal - Association of Official Analytical Chemists, 67(3), 557-562 (1984-05-01)
A rapid and sensitive procedure is described for determining 4 N-nitrosodialkylamines (dimethyl, diethyl, dipropyl, and dibutyl) and the N-nitroso analogs of piperidine, pyrrolidine, and morpholine in animal feed. The volatile N-nitrosamines were isolated by using a modified high temperature purge
K E Appel et al.
IARC scientific publications, (57)(57), 443-451 (1984-01-01)
Nitrite was formed on incubation of N-nitrosamines with both microsomal systems and a reconstituted system consisting of cytochrome P-450 and NADPH P-450 reductase from pig liver. Nitrite was not obtained when the nitrosamines were incubated with NADPH P-450 reductase alone
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