48554
N-亚硝基二正丙胺
analytical standard
别名:
NDPA
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关于此项目
经验公式（希尔记法）:
C6H14N2O
化学文摘社编号:
分子量:
130.19
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
210-698-0
MDL number:
NACRES:
NA.24
产品名称
N-亚硝基二正丙胺, analytical standard
InChI key
YLKFDHTUAUWZPQ-UHFFFAOYSA-N
InChI
1S/C6H14N2O/c1-3-5-8(7-9)6-4-2/h3-6H2,1-2H3
SMILES string
CCCN(CCC)N=O
grade
analytical standard
CofA
current certificate can be downloaded
packaging
ampule of 100 mg
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
cleaning products
cosmetics
environmental
food and beverages
personal care
format
neat
storage temp.
2-30°C
Quality Level
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Application
N-亚硝基二正-丙基胺可用作分析参考标准品，用于通过气相色谱-三重四极杆质谱测定废水样品中的分析物。
Analysis Note
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
General description
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodi-n-propylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosodi-n-propylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Development and validation of GC-FID method for the determination of volatile N-nitrosamines in meat
Al-Kaseem M, et al.
International Journal of Pharmaceutical Sciences Review and Research, 25, 59-64 (2014)
A new method for quantifying N-nitrosamines in wastewater samples by gas chromatography?triple quadrupole mass spectrometry.
Yoon S, et al.
Talanta, 97, 256-261 (2012)
J G Farrelly et al.
Carcinogenesis, 5(8), 1015-1019 (1984-08-01)
Nitrosodiallylamine has been reported to be non-carcinogenic in rats while nitrosodipropylamine and nitrosodiethanolamine are liver carcinogens. That nitrosodipropylamine is metabolized at the alpha-position by liver microsomes from Fischer-344 rats supports the widely held contention that such metabolism is responsible for
S M Billedeau et al.
Journal - Association of Official Analytical Chemists, 67(3), 557-562 (1984-05-01)
A rapid and sensitive procedure is described for determining 4 N-nitrosodialkylamines (dimethyl, diethyl, dipropyl, and dibutyl) and the N-nitroso analogs of piperidine, pyrrolidine, and morpholine in animal feed. The volatile N-nitrosamines were isolated by using a modified high temperature purge
D Wotherspoon et al.
Journal - Association of Official Analytical Chemists, 71(2), 333-336 (1988-03-01)
A quick method for determining N-nitrosodipropylamine (NDPA) levels in trifluralin emulsifiable concentrate formulations is described. At least 18 samples can be analyzed at one time in a minimum of fumehood space, with up to 90% savings on solvents and materials.
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