48554
N-亚硝基二正丙胺
analytical standard
别名:
NDPA
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关于此项目
经验公式（希尔记法）:
C6H14N2O
化学文摘社编号:
分子量:
130.19
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
210-698-0
MDL number:
NACRES:
NA.24
InChI key
YLKFDHTUAUWZPQ-UHFFFAOYSA-N
InChI
1S/C6H14N2O/c1-3-5-8(7-9)6-4-2/h3-6H2,1-2H3
SMILES string
CCCN(CCC)N=O
grade
analytical standard
CofA
current certificate can be downloaded
packaging
ampule of 100 mg
manufacturer/tradename
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
cleaning products
cosmetics
environmental
food and beverages
personal care
format
neat
storage temp.
2-30°C
Quality Level
General description
Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodi-n-propylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
N-Nitrosodi-n-propylamine solution is commonly employed as a reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.
Application
N-亚硝基二正-丙基胺可用作分析参考标准品，用于通过气相色谱-三重四极杆质谱测定废水样品中的分析物。
Analysis Note
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Development and validation of GC-FID method for the determination of volatile N-nitrosamines in meat
Al-Kaseem M, et al.
International Journal of Pharmaceutical Sciences Review and Research, 25, 59-64 (2014)
A new method for quantifying N-nitrosamines in wastewater samples by gas chromatography?triple quadrupole mass spectrometry.
Yoon S, et al.
Talanta, 97, 256-261 (2012)
K E Appel et al.
IARC scientific publications, (57)(57), 443-451 (1984-01-01)
Nitrite was formed on incubation of N-nitrosamines with both microsomal systems and a reconstituted system consisting of cytochrome P-450 and NADPH P-450 reductase from pig liver. Nitrite was not obtained when the nitrosamines were incubated with NADPH P-450 reductase alone
D Wotherspoon et al.
Journal - Association of Official Analytical Chemists, 71(2), 333-336 (1988-03-01)
A quick method for determining N-nitrosodipropylamine (NDPA) levels in trifluralin emulsifiable concentrate formulations is described. At least 18 samples can be analyzed at one time in a minimum of fumehood space, with up to 90% savings on solvents and materials.
S M Billedeau et al.
Journal - Association of Official Analytical Chemists, 67(3), 557-562 (1984-05-01)
A rapid and sensitive procedure is described for determining 4 N-nitrosodialkylamines (dimethyl, diethyl, dipropyl, and dibutyl) and the N-nitroso analogs of piperidine, pyrrolidine, and morpholine in animal feed. The volatile N-nitrosamines were isolated by using a modified high temperature purge
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