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Merck
CN

1268750

USP

依托咪酯

United States Pharmacopeia (USP) Reference Standard

别名:

(R)-1-(α-甲苄基)咪唑-5-甲酸乙酯, Amidate, R16659

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关于此项目

经验公式（希尔记法）:
C14H16N2O2
化学文摘社编号:
33125-97-2
分子量:
244.29
NACRES:
NA.24
PubChem Substance ID:
329749815
UNSPSC Code:
41116107
MDL number:
MFCD00869295

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InChI

1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1

SMILES string

CCOC(=O)c1cncn1[C@H](C)c2ccccc2

InChI key

NPUKDXXFDDZOKR-LLVKDONJSA-N

grade

pharmaceutical primary standard

API family

etomidate

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

依托咪酯(Etomidate)是一种全身麻醉药；可激活GABAA 信号通路
依托咪酯(Etomidate)是一种全身麻醉药；可激活GABAA信号通路。已有研究，依托咪酯对大鼠脑和脊髓中链脲菌素诱导(STZ-induced)的高血糖具有神经保护作用。依托咪酯治疗对神经组织具有抗糖尿病氧化损伤的神经保护作用。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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