产品名称
溴吡斯的明, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
SMILES string
[Br-].CN(C)C(=O)Oc1ccc[n+](C)c1
InChI key
VNYBTNPBYXSMOO-UHFFFAOYSA-M
grade
pharmaceutical primary standard
API family
pyridostigmine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... ACHE(43)
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Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application
Pyridostigmine bromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Pyridostigmine Bromide Injection
- Pyridostigmine Bromide Oral Solution
- Pyridostigmine Bromide Tablets
Biochem/physiol Actions
Acetylcholinesterase inhibitor.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Alternating superior and inferior oblique myokymia.
Trevor A Smith et al.
JAMA ophthalmology, 132(7), 898-899 (2014-07-11)
P A Ferchmin et al.
Neurotoxicology, 44, 80-90 (2014-06-15)
Many organophosphorous esters synthesized for applications in industry, agriculture, or warfare irreversibly inhibit acetylcholinesterase, and acute poisoning with these compounds causes life-threatening cholinergic overstimulation. Following classical emergency treatment with atropine, an oxime, and a benzodiazepine, surviving victims often suffer brain
Marie Vandeput et al.
Journal of pharmaceutical and biomedical analysis, 102, 267-275 (2014-12-03)
A commercially available thin-layer flow-through amperometric detector, with the sensing block customized in an original design, was applied to the screening of drug compounds known as acetylcholinesterase (AChE) inhibitors. AChE from electric eel was covalently immobilized onto a cysteamine modified
Zuchra Zakirova et al.
PloS one, 10(3), e0119579-e0119579 (2015-03-19)
Gulf War Illness (GWI) is a chronic multisymptom illness with a central nervous system component such as memory deficits, neurological, and musculoskeletal problems. There are ample data that demonstrate that exposure to Gulf War (GW) agents, such as pyridostigmine bromide
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