SMC^® Human IFN-α2 High Sensitivity Immunoassay Kit

Human Interferon alpha-2 (IFNa2) is a cytokine belonging to the IFN family exhibiting antiviral, antitumor and antiproliferative effects on immune response. IFNa2 is secreted by viral infected cells and acts to inhibit viral infection. It has been shown to play a role in autoimmune diseases such as lupus and myositis. The mechanisms of action underlying the pathogenic role that IFNa and IFNß play in autoimmunity is not well understood but elucidating their role will lead to a better understanding of these cytokines in chronic inflammation and immunity.

Inflammatory Disease / Immune Response / Autoimmune Disease

96 well assay

• Sensitivity: LLOQ 60 fg/mL* (SMCxPRO^® Instrument)
• Standard Curve Range: 15-80,000 fg/mL
• Intra-assay CV: <15%
• Inter-assay CV: <20%
• Linearity: Serum: 90% Plasma: 102%
• Recovery: Serum: 102% Plasma: 96%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.

Although IFN-α2 was detectable in rat, pig, non-human primate, canine, and feline samples, the assay has not been verified for these species.

FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany

SMC is a registered trademark of Singulex

SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.