MILLIPLEX® Multiplex Serology Solutions
MILLIPLEX® serology assays, powered by Luminex® xMAP® technology, redefine multiplex analysis by combining high-throughput capabilities with unparalleled flexibility, enabling researchers to decode complex profiles efficiently.
Autoantibodies are antibodies that mistakenly react with self-antigens, targeting the body’s own cells, tissues, and organs. Autoantibodies can occur in healthy individuals and are commonly associated with a variety of diseases or disease manifestations including autoimmune disorders, cancer, and neurological conditions. MILLIPLEX® assays can be used to evaluate these immune responses through the simultaneous detection of multiple autoantibodies. Our catalog includes specialized kits for:
- Autoimmune Autoantibodies – Track immunological signatures from dysregulated apoptosis and impaired cellular debris clearance that may indicate disease activity, progression, and scientific associations across autoimmune diseases.
- Cancer Autoantibodies – Harness the unique properties of autoantibodies to tumor-associated antigens to advance cancer biomarker discovery.
- Neurodegenerative Autoantibodies – Detect these autoantibodies in blood or cerebrospinal fluid (CSF) to obtain valuable insights into the autoimmune processes linked to neurodegenerative diseases.
- Cytokine Autoantibodies – Investigate prevalent immune modulators present in healthy individuals and individuals with acquired immunodeficiency and autoimmune diseases.
Streamline Your Serology Testing with the MILLIPLEX® Dual Reporter Reagent Pack
This innovative Dual Reporter Autoantibody Reagent Pack enables simultaneous detection of both IgG and IgM antibodies on a single bead, providing a comprehensive view of the immune response. This market-exclusive kit, compatible with MILLIPLEX® serology assays and the xMAP® INTELLIFLEX® DR-SE system, not only enhances throughput but also streamlines lab workflows, ensuring reliable results.
Figure 1.IgG and IgM autoantibodies in serum and plasma detected using the Dual Reporter Reagent Pack with the MILLIPLEX® Human Neurodegenerative Autoantibody Panel (Cat. No. HNDGAB-220K). Samples from donors with multiple sclerosis, stroke, Alzheimer’s disease, and Parkinson’s disease as well as samples from apparently healthy donors were tested (n=56 total).
Figure 2.The xMAP® INTELLIFLEX® system for MILLIPLEX® multiplex biomarker detection.
Next-Gen Multiplexing with the xMAP® INTELLIFLEX® DR-SE System
This compact flow-based platform integrates dual-laser technology and an intuitive touchscreen interface, streamlining data acquisition and minimizing lab footprint. The dual laser enables measurement of both IgG and IgM antibody classes in a single run.
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