Merck
CN

ABCC1

ATP-binding cassette, sub-family C (CFTR/MRP), member 1

别名:
ABC29, ABCC, GS-X, MRP, MRP1
物种:
UniProtKB ID:
基因ID:
  • Human(4363) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
  • Mouse(17250) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Rat(24565) ATP-binding cassette, subfamily C (CFTR/MRP), member 1
  • naked mole-rat(101725452) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • sheep(101110991) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • domestic cat(101101279) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Horse(791240) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • chicken(395416) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Domestic Rabbit(100345841) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Zebrafish(100002010) ATP-binding cassette, sub-family C, member 1
  • cow(281588) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • domestic guinea pig(100734674) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • dog(403453) ATP-binding cassette, sub-family C (CFTR/MRP), member 1

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Antibodies

货号
说明
物种反应性
应用
Anti-MRP1 Antibody, clone QCRL-1, clone QCRL-1, Chemicon®, from mouse,
物种反应性
human
应用
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-MRP1 antibody,Mouse monoclonal, clone QCRL-1, purified from hybridoma cell culture,
物种反应性
human
应用
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
抗-ABCC1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-MRP1/ABCC1 Antibody, clone 0J6M2, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
immunohistochemistry
western blot
Anti-MRP1 Antibody, clone MRPm5, clone MRPm5, Chemicon®, from mouse,
物种反应性
human
应用
flow cytometry
immunohistochemistry

western blot

Cell Lines

货号
说明
物种
MRP1 Knockout Caco-2 Cells, one vial,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
氯喹 二磷酸盐, powder or crystals, 98.5-101.0% (EP),
物种
human

Proteins

货号
说明
物种
SB-MRP1-Sf9, membrane preparation for Vesicular Transport Assays, recombinant, expressed in baculovirus infected Sf9 cells,
物种
human
MRP1 human, membrane preparation for ATPase Assay, recombinant, expressed in baculovirus infected Sf9 cells,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human ABCC1,
物种
human
MISSION® esiRNA, targeting mouse Abcc1,
物种
mouse