CN
CCL5
chemokine (C-C motif) ligand 5
别名:
D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP
物种:
Human CCL5 (6352), Mouse Ccl5 (20304), Rat Ccl5 (81780), sheep CCL5 (101115553), domestic guinea pig Ccl5 (100135495), naked mole-rat Ccl5 (101712384), chicken CCL5 (417465), cow CCL5 (327712), Horse CCL5 (100033925), domestic cat CCL5 (493689)
UniProtKB ID:
基因ID:
- Human(6352) Summary: This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of two N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
- Mouse(20304) chemokine (C-C motif) ligand 5
- Rat(81780) chemokine (C-C motif) ligand 5
- sheep(101115553) chemokine (C-C motif) ligand 5
- domestic guinea pig(100135495) chemokine (C-C motif) ligand 5
- naked mole-rat(101712384) chemokine (C-C motif) ligand 5
- chicken(417465) chemokine (C-C motif) ligand 5
- cow(327712) chemokine (C-C motif) ligand 5
- Horse(100033925) chemokine (C-C motif) ligand 5
- domestic cat(493689) chemokine (C-C motif) ligand 5
- dog(403522) chemokine (C-C motif) ligand 5
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Monoclonal Anti-RANTES antibody produced in rat, clone 53405.111, purified immunoglobulin, lyophilized powder,
物种反应性
mouse
应用
immunocytochemistry
neutralization
neutralization
Anti-RANTES antibody produced in goat, affinity isolated antibody, lyophilized powder,
物种反应性
human
应用
immunohistochemistry
neutralization
western blot
neutralization
western blot
Proteins
esiRNA
货号
说明
物种