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Merck
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EQCYTMAG-93K

MILLIPLEX® Equine Cytokine/Chemokine Panel

Configurable Equine Cyokine/Chemokine 23-Plex Panel

别名:

Equine cytokine panel, Luminex equine cytokine multiplex kit, Millipore horse cytokine kit, horse inflammation assay

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关于此项目

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

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产品名称

MILLIPLEX® Equine Cytokine/Chemokine Panel, Configurable Equine Cyokine/Chemokine 23-Plex Panel

Quality Level

200

species reactivity

horse

assay range

accuracy: 74%
(IL-17a)
accuracy: 76%
(IL-6)
accuracy: 78%
(FGF-2)
accuracy: 82%
(G-CSF)
accuracy: 83%
(IFNγ)
accuracy: 83%
(IL-12 (p70))
accuracy: 85%
(IL-13)
accuracy: 86%
(IL-10)
accuracy: 88%
(RANTES/CCL5)
accuracy: 89%
(IL-8/CXCL8)
accuracy: 90%
(IL-2)
accuracy: 90%
(MCP-1)
accuracy: 91%
(Fractalkine/CS3CL1)
accuracy: 92%
(IL-5)
accuracy: 93%
(Eotaxin/CCL11)
accuracy: 97%
(GRO)
sensitivity: 1.4 pg/mL
(IL-6)
sensitivity: 10.6 pg/mL
(IL-5)
sensitivity: 13.5 pg/mL
(IL-2)
sensitivity: 15.4 pg/mL
(IL-17A)
sensitivity: 16.3 pg/mL
(FGF-2)
sensitivity: 16.7 pg/mL
(IP-10)
sensitivity: 165 pg/mL
(IFNγ)
sensitivity: 25.3 pg/mL
(IL-18)
sensitivity: 29.3 pg/mL
(IL-1β)
sensitivity: 3.9 pg/mL
(RANTES/CCL5)
sensitivity: 3.94 pg/mL
(GM-CSF)
sensitivity: 340 pg/mL
(G-CSF)
sensitivity: 355 pg/mL
(IL-4)
sensitivity: 39-130 pg/mL
(IL-13)
sensitivity: 39.1 pg/mL
(IL-1α)
sensitivity: 399 ng/mL
(MCP-1)
sensitivity: 457 pg/mL
(Fractalkine/CS3CL1)
sensitivity: 49.2 pg/mL
(IL-12 (p70))
sensitivity: 5.2 pg/mL
(TNFα)
sensitivity: 62.5 pg/mL
(IL-10)
sensitivity: 7.8 pg/mL
(GRO)
sensitivity: 74.3 pg/mL
(IL-8/CXCL8)
sensitivity: 8.3 pg/mL
(Eotaxin/CCL11)
standard curve range: 15-15,000 pg/mL
(IL-17A)
standard curve range: 15-15,000 pg/mL
(IL-2)
standard curve range: 15-15,000 pg/mL
(IL-5)
standard curve range: 15-15,000 pg/mL
(IL-6)
standard curve range: 15-15,000 pg/mL
(IP-10)
standard curve range: 16.3 pg/mL
(FGF-2)
standard curve range: 29-30,000 pg/mL
(IL-1β)
standard curve range: 293-300,000 pg/mL
(IL-4)
standard curve range: 34-35,000 pg/mL
(IL-18)
standard curve range: 340 pg/mL
(G-CSF)
standard curve range: 342-350,000 ng/mL
(MCP-1)
standard curve range: 39-40,000 pg/mL
(IL-12 (p70))
standard curve range: 39-40,000 pg/mL
(IL-13)
standard curve range: 4-4,000 pg/mL
(TNFα)
standard curve range: 457 pg/mL
(Fractalkine/CS3CL1)
standard curve range: 488-500,000 pg/mL
(IFNγ)
standard curve range: 49-50,000 pg/mL
(IL-10)
standard curve range: 5-5,000 pg/mL
(GM-CSF)
standard curve range: 5-5,000 pg/mL
(RANTES/CCL5)
standard curve range: 59-60,000 pg/mL
(IL-1α)
standard curve range: 59-60,000 pg/mL
(IL-8/CXCL8)
standard curve range: 6-6,000 pg/mL
(GRO)
standard curve range: 8.3 pg/mL
(Eotaxin/CCL11)

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

相关类别

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 23 analytes in equine serum, plasma, and cell culture supernatants.

Analytes included: Eotaxin/CCL11, FGF-2, Fractalkine/CX3CL1, G-CSF, GM-CSF, GRO/KC, IFN-γ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12 (p70), IL-13, IL-17A, IL-18, IP-10 (CXCL10), MCP-1, RANTES (CCL5), TNF-α

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Biochem/physiol Actions

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

  • Comprehensive 23-plex Cytokine and Chemokine Panel: Simultaneously quantify 23 critical immune mediators (including Eotaxin, FGF-2, G-CSF, IL-1α, IL-6, IL-10, TNFα, and more) in equine serum, plasma, or culture supernatant samples, providing a holistic view of the equine immune response.
  • High-Throughput 96-well Format: Analyze up to 38 samples in duplicate, maximizing laboratory efficiency and sample utilization while minimizing reagent costs and hands-on time.
  • In-Depth Immune Profiling: Investigate the immune response in equine models of infectious diseases, osteoarthritis, respiratory diseases, and other conditions, facilitating a better understanding of disease mechanisms and potential therapeutic targets.
  • Enhanced Statistical Power: Generate multi-parameter datasets from individual samples, improving experimental design and enabling sophisticated statistical analyses for publication-quality research outcomes.

General description

Researching horse cytokines and chemokines is pivotal for advancing our understanding of equine immunology and the underlying mechanisms of various diseases. By investigating the roles and interactions of these signaling molecules, scientists can uncover critical insights into inflammatory processes, immune responses, and the pathophysiology of equine conditions. This knowledge not only enhances our fundamental understanding of equine biology but also drives the development of targeted therapeutic strategies and interventions in equine medicine.

Preparation Note

Recommended storage for kit components is 2 - 8°C.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

wgk

WGK 3

法规信息

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Protocol-MILLIPLEX® Equine Cytokine/Chemokine Magnetic Bead Panel
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