Merck
CN

HTR1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

别名:
5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12
物种:
UniProtKB ID:
基因ID:
  • Human(3351) Summary: The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]
  • Mouse(15551) 5-hydroxytryptamine (serotonin) receptor 1B
  • Rat(25075) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • chicken(421858) 5-hydroxytryptamine (serotonin) receptor 1B
  • Zebrafish(561647) 5-hydroxytryptamine (serotonin) receptor 1B
  • dog(403741) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • cow(317707) 5-hydroxytryptamine (serotonin) receptor 1B
  • Horse(100009680) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic cat(100144391) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • Domestic Rabbit(100009594) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • sheep(101111375) 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
  • domestic guinea pig(100135543) 5-hydroxytryptamine (serotonin) receptor 1B

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Small Molecule - Agonist

货号
说明
物种
苯甲酸利扎曲普坦, Pharmaceutical Secondary Standards; Certified Reference Material,
物种
human
利扎曲坦 苯甲酸盐, ≥98% (HPLC),
物种
human
Frovatriptan succinate monohydrate, ≥97% (HPLC),
物种
human
Sumatriptan succinate, European Pharmacopoeia (EP) Reference Standard,
物种
human
佐米曲普坦, United States Pharmacopeia (USP) Reference Standard,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
DCEBIO, ≥98% (HPLC), solid,
物种
human

Small Molecule - Antagonist

货号
说明
物种
GR 127935 hydrochloride hydrate, >98% (HPLC), powder,
物种
human
甲硫替平 甲磺酸盐, ≥98% (HPLC), solid,
物种
human
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
5-羧酰胺色胺 马来酸盐, powder, ≥98% (HPLC),
物种
human, rat
氨磺必利, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-Serotonin Receptor 1B Antibody, clone 1C2.1, clone 1C2.1, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-5-HT-1B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry
抗-HTR1B 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
Anti-HTR1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-Serotonin Receptor 1B/HTR1B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human, mouse, rat
应用
ELISA
western blot

Small Molecule - Blocker

货号
说明
物种
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
曲唑酮 盐酸盐, ≥99% (HPLC), powder,
物种
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物种
human
氟西汀 盐酸盐, solid,
物种
human
氢溴酸西酞普兰 氢溴酸盐, ≥98% (HPLC),
物种
human
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物种
human

Small Molecule - Ligand

货号
说明
物种
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物种
human

Small Molecule - Metabolite

货号
说明
物种
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物种
human

Small Molecule - Precursor

货号
说明
物种
5-羟基L-色氨酸, powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Htr1b,
物种
mouse