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Y0000022

Sumatriptan succinate

Name: Sumatriptan succinate
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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别名:

3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate, GR-43175

经验公式（希尔记法）:

C₁₄H₂₁N₃O₂S · C₄H₆O₄

CAS号:

103628-48-4

分子量:

413.49

MDL编号:

MFCD00902856

PubChem化学物质编号:

329830818

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

sumatriptan

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

−20°C

SMILES字符串

OC(=O)CCC(O)=O.CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1

InChI

1S/C14H21N3O2S.C4H6O4/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3;5-3(6)1-2-4(7)8/h4-5,8-9,15-16H,6-7,10H2,1-3H3;1-2H2,(H,5,6)(H,7,8)

InChI key

PORMUFZNYQJOEI-UHFFFAOYSA-N

基因信息

human ... HTR1B(3351) , HTR1D(3352)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Sumatriptan succinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化/生理作用

Sumatriptan succinate is a 5-HT1 serotonin receptor agonist.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

警示用语：

Warning

危险声明

H361d - H412

预防措施声明

P202 - P273 - P280 - P308 + P313 - P405 - P501

危险分类

Aquatic Chronic 3 - Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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索取COA

A randomized controlled trial of a comprehensive migraine intervention prior to discharge from an emergency department.

Benjamin W Friedman et al.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 19(10), 1151-1157 (2012-09-22)

Patients who use an emergency department (ED) for acute migraine headaches have higher migraine disability scores, lower socioeconomic status, and are unlikely to have used a migraine-specific medication prior to presentation to the ED. The objective was to determine if

Use of scintigraphy to evaluate gastric accommodation and emptying: comparison with barostat.

Toshihiko Tomita et al.

Journal of gastroenterology and hepatology, 28(1), 106-111 (2012-09-20)

Scintigraphy is a useful noninvasive technique for assessment of gastric motility, especially emptying, but there is little knowledge of use of the technique to assess gastric accommodation. Therefore, to clarify the usefulness of scintigraphy as a technique for assessing gastric

Influence of sumatriptan on gastric accommodation and on antral contraction in healthy subjects assessed by ultrasonography.

Y Sekino et al.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 24(12), 1083-e564-1083-e564 (2012-08-14)

Oral sumatriptan administration has been reported to delay gastric emptying after liquid meals. The aim of this study was to determine whether delayed gastric emptying is caused by enhanced gastric accommodation, impaired antral contractions, or both using ultrasonography. Ten healthy

Effect of sumatriptan on gastric emptying: a crossover study using the BreathID system.

Yasunari Sakamoto et al.

World journal of gastroenterology, 18(26), 3415-3419 (2012-07-19)

To determine the effect of oral sumatriptan on gastric emptying using a continuous ¹³C breath test (BreathID system). Ten healthy male volunteers participated in this randomized, 2-way crossover study. The subjects fasted overnight and were randomly assigned to receive a

Rapid determination of sumatriptan in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and its application to clinical pharmacokinetic study.

Jeong Ju Seo et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 919-920, 38-42 (2013-02-16)

A sensitive and simple detection method coupling ultra-performance liquid chromatography with tandem mass spectrometry was developed and validated to analyze sumatriptan levels in human plasma. The plasma sample preparations for the analysis were based on liquid-liquid extraction with ethyl acetate

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