CN

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

别名:

5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3

物种:

Human HTR3A (3359), Mouse Htr3a (15561), Rat Htr3a (79246), Domestic Rabbit HTR3A (100009570), chicken HTR3A (428247), domestic guinea pig Htr3a (100135547), Horse HTR3A (100009690), naked mole-rat Htr3a (101714088), sheep HTR3A (101110536), dog HTR3A (489399) ...展开

UniProtKB ID:

P46098, B4DSY6, G5E986, O60854, Q7KZM7, Q99918, Q9BSZ9

基因ID:

Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

产品 (53)
同行评审论文 (66)

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Small Molecule - Agonist

货号

说明

物种

甲氧氯普胺, VETRANAL^®, analytical standard,

物种

human

甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard,

物种

human

甲氧氯普胺盐酸盐, British Pharmacopoeia (BP) Reference Standard,

物种

human

SR 57227A, solid,

物种

human

甲氧氯普胺盐酸盐, solid,

物种

human

Small Molecule - Allosteric Modulator

货号

说明

物种

DCEBIO, ≥98% (HPLC), solid,

物种

human

Small Molecule - Antagonist

货号

说明

物种

3-(2-氨乙酸)吲哚盐酸盐, powder,

物种

human

盐酸昂丹司琼, Pharmaceutical Secondary Standard; Certified Reference Material,

物种

human

5-羟色胺肌酸酐硫酸盐一水合物, powder,

物种

human

昂丹司琼盐酸盐二水合物, ≥98% (HPLC), powder,

物种

human

昂丹司琼盐酸盐二水合物, United States Pharmacopeia (USP) Reference Standard,

物种

human

Antibodies

货号

说明

物种反应性

应用

抗血清素受体3A / HTR3A, from rabbit, purified by affinity chromatography,

物种反应性

human

应用

immunohistochemistry
western blot

Anti-HTR3A antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody,

物种反应性

human

应用

immunohistochemistry

Small Molecule - Blocker

货号

说明

物种

三甲丙咪嗪标准液马来酸盐, ≥98% (TLC), powder,

物种

human

Small Molecule - Inhibitor

货号

说明

物种

S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,

物种

human

R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,

物种

human

F132

氟西汀盐酸盐, solid,

物种

human

盐酸舍曲林盐酸盐, ≥98% (HPLC),

物种

human

氢溴酸西酞普兰氢溴酸盐, ≥98% (HPLC),

物种

human

Small Molecule - Ligand

货号

说明

物种

Nω-Methyl-5-hydroxytryptamine oxalate salt, ≥90% (HPLC),

物种

human

Small Molecule - Metabolite

货号

说明

物种

5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,

物种

human

Small Molecule - Precursor

货号

说明

物种

5-羟基L-色氨酸, powder,

物种

human

esiRNA

货号

说明

物种

MISSION^® esiRNA, targeting mouse Htr3a,

物种

mouse

MISSION^® esiRNA, targeting human HTR3A,

物种

human