Merck
CN

NOS1

nitric oxide synthase 1 (neuronal)

别名:
IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS
物种:
UniProtKB ID:
基因ID:
  • Human(4842) Summary: The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
  • Mouse(18125) nitric oxide synthase 1, neuronal
  • Rat(24598) nitric oxide synthase 1, neuronal
  • Domestic Rabbit(100009243) nitric oxide synthase 1 (neuronal)
  • naked mole-rat(101711993) nitric oxide synthase 1 (neuronal)
  • cow(536132) nitric oxide synthase 1 (neuronal)
  • domestic cat(101100342) nitric oxide synthase 1 (neuronal)
  • Zebrafish(60658) nitric oxide synthase 1 (neuronal)
  • Horse(100051079) nitric oxide synthase 1 (neuronal)
  • dog(477498) nitric oxide synthase 1 (neuronal)
  • chicken(427721) nitric oxide synthase 1 (neuronal)
  • domestic guinea pig(100729682) nitric oxide synthase 1 (neuronal)

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Small Molecule - Antagonist

货号
说明
物种
吡咯烷二硫代氨基甲酸铵, ~99%,
物种
human
褪黑素, powder, ≥98% (TLC),
物种
human
Nω-硝基-L-精氨酸, ≥98% (TLC),
物种
rat, mouse, human
(±)-沙利度胺, ≥98%, powder,
物种
human, mouse, rat
喷他脒 羟乙基磺酸盐, powder,
物种
human

Antibodies

货号
说明
物种反应性
应用
抗硝基酪氨酸 兔抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
wide range
应用
ELISA
immunofluorescence

immunohistochemistry

microarray

western blot
抗硝基酪氨酸抗体, Upstate®, from rabbit,
物种反应性
all
应用
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
抗硝基酪氨酸抗体, Chemicon®, from rabbit,
物种反应性
all, human, mouse
应用
immunohistochemistry
western blot
Anti-Nitric Oxide Synthase I Antibody, serum, Chemicon®,
物种反应性
human, monkey, mouse, rat, sheep
应用
immunohistochemistry
western blot
Anti-Nitrotyrosine Antibody, clone 2A8.2, clone 2A8.2, Chemicon®, from mouse,
物种反应性
all
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
亚精胺 三盐酸盐, ≥98% (TLC),
物种
human
4-硝基儿茶酚, ≥96.0%,
物种
rat
5-甲基-2-硝基苯胺, 95%,
物种
rat
L-精氨酸, reagent grade, ≥98%,
物种
rat, human
2,6-二--丁基-4-甲基苯酚, ≥99.0% (GC), powder,
物种
rat, human

Kits

货号
说明
物种
一氧化氮合酶检测系统,荧光法, sufficient for 200 reactions,
物种
human

Small Molecule - Precursor

货号
说明
物种
L-精氨酸, reagent grade, ≥98%,
物种
rat, human
L-精氨酸, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%,
物种
rat, human
L-精氨酸, BioUltra, ≥99.5% (NT),
物种
rat, human
L-精氨酸, 99%, FCC, FG,
物种
rat, human
L-精氨酸, ,
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Nos1,
物种
mouse