Merck
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PPARG

peroxisome proliferator-activated receptor gamma

别名:
CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
物种:
UniProtKB ID:
基因ID:
  • Human(5468) Summary: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(19016) peroxisome proliferator activated receptor gamma
  • Rat(25664) peroxisome proliferator-activated receptor gamma
  • Zebrafish(557037) peroxisome proliferator activated receptor gamma
  • chicken(373928) peroxisome proliferator-activated receptor gamma
  • cow(281993) peroxisome proliferator-activated receptor gamma
  • naked mole-rat(101711078) peroxisome proliferator-activated receptor gamma
  • Goat(100861309) peroxisome proliferator-activated receptor gamma
  • domestic cat(100049014) peroxisome proliferator-activated receptor gamma
  • domestic cat(101095161) peroxisome proliferator-activated receptor gamma
  • domestic guinea pig(100729138) peroxisome proliferator-activated receptor gamma
  • sheep(443513) peroxisome proliferator-activated receptor gamma
  • dog(403606) peroxisome proliferator-activated receptor gamma

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Small Molecule - Activator

货号
说明
物种
Ciglitizone, ≥98% (HPLC),
物种
mouse, human
4-氯苯氧异丁酸, 97%,
物种
mouse, human
WY-14643, ,
物种
rat, human, mouse
苯扎贝特, ≥98%, solid,
物种
mouse, human

Small Molecule - Agonist

货号
说明
物种
罗格列酮, ≥98% (HPLC),
物种
human
吡格列酮, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
吡格列酮, ,
物种
human
吡格列酮 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
吡格列酮 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
GW9662, >98% (HPLC),
物种
human
Ciglitizone, ≥98% (HPLC),
物种
mouse, human
GW0742, ≥98% (HPLC),
物种
human
顺式-5,8,11,14,17-二十碳五烯酸, ≥99%,
物种
mouse, human, rat
CDDO 甲酯, ≥98% (HPLC),
物种
human

Antibodies

货号
说明
物种反应性
应用
抗PPAR-γ抗体, from rabbit, purified by affinity chromatography,
物种反应性
canine, feline, human, monkey, mouse, porcine
应用
immunocytochemistry
western blot
Anti-PPAR gamma antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
抗 PPAR-γ 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
抗-PPAR γ1和2抗体,磷酸特异性(Ser112), ascites fluid, Chemicon®,
物种反应性
human, mouse
应用
ELISA
immunocytochemistry

western blot
Anti-PPAR γ Antibody, isoform 1&2, ascites fluid, clone 1H4, Chemicon®,
物种反应性
human, mouse
应用
ELISA
immunocytochemistry

western blot

Proteins

货号
说明
物种
PPAR, γ 人, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
物种
human
PPAR γ, ligand binding domain (204-477), GST tagged human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PPARG,
物种
human
MISSION® esiRNA, targeting mouse Pparg,
物种
mouse