Merck
CN

PTGDR

prostaglandin D2 receptor (DP)

别名:
AS1, ASRT1, DP, DP1, PTGDR1
物种:
Human PTGDR (5729), Mouse Ptgdr (19214), Rat Ptgdr (498475), naked mole-rat Ptgdr (101710975), domestic cat PTGDR (101098059), cow PTGDR (515331), dog PTGDR (610845), domestic guinea pig Ptgdr (100721994)
UniProtKB ID:
Q13258, Q13250, Q13251, Q1ZZ52
基因ID:
  • Human(5729) Summary: The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. [provided by RefSeq, Jul 2008]
  • Mouse(19214) prostaglandin D receptor
  • Rat(498475) prostaglandin D2 receptor-like
  • naked mole-rat(101710975) prostaglandin D2 receptor (DP)
  • domestic cat(101098059) prostaglandin D2 receptor (DP)
  • cow(515331) prostaglandin D2 receptor (DP)
  • dog(610845) prostaglandin D2 receptor (DP)
  • domestic guinea pig(100721994) prostaglandin D2 receptor (DP)

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Small Molecule - Antagonist

货号
说明
物种
I7378
吲哚美辛, 98.5-100.5% (in accordance with EP),
物种
human, mouse, rat
I8280
吲哚美辛, meets USP testing specifications,
物种
human, mouse, rat

Antibodies

货号
说明
物种反应性
应用
SAB1406332
Anti-PTGDR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
flow cytometry
western blot
SAB4502478
Anti-PTGDR antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
western blot
SAB1401319
Anti-PTGDR antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
HPA049668
Anti-PTGDR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
I7378
吲哚美辛, 98.5-100.5% (in accordance with EP),
物种
human, mouse, rat

Proteins

货号
说明
物种
HTS091M
ChemiSCREEN Human DP Prostanoid Receptor Membrane Preparation, Human DP GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
物种
human