Merck
CN

RRM2B

ribonucleotide reductase M2 B (TP53 inducible)

别名:
MTDPS8A, MTDPS8B, P53R2
物种:
UniProtKB ID:
基因ID:
  • Human(50484) Summary: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
  • Mouse(382985) ribonucleotide reductase M2 B (TP53 inducible)
  • Rat(299976) ribonucleotide reductase M2 B (TP53 inducible)
  • naked mole-rat(101718446) ribonucleotide reductase M2 B (TP53 inducible)
  • cow(528960) ribonucleotide reductase M2 B (TP53 inducible)
  • sheep(101123639) ribonucleotide reductase M2 B (TP53 inducible)
  • domestic cat(101099777) ribonucleotide reductase M2 B (TP53 inducible)
  • Zebrafish(368909) ribonucleotide reductase M2 b
  • domestic guinea pig(100715485) ribonucleotide reductase M2 B (TP53 inducible)
  • Horse(100062030) ribonucleotide reductase M2 B (TP53 inducible)
  • dog(481988) ribonucleotide reductase M2 B (TP53 inducible)
  • chicken(420253) ribonucleotide reductase M2 B (TP53 inducible)

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Antibodies

货号
说明
物种反应性
应用
Anti-P53R2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-RRM2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Monoclonal Anti-RRM2B antibody produced in mouse, clone 6C1, ascites fluid,
物种反应性
human
应用
ELISA
western blot

Small Molecule - Inhibitor

货号
说明
物种
羟基脲, United States Pharmacopeia (USP) Reference Standard,
物种
human
羟基脲, European Pharmacopoeia (EP) Reference Standard,
物种
human
羟基脲, British Pharmacopoeia (BP) Reference Standard,
物种
human
羟基脲, Vetec, reagent grade, ≥98%,
物种
human
羟基脲, 98%, powder,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human RRM2B,
物种
human