产品名称
羟基脲, British Pharmacopoeia (BP) Reference Standard
SMILES string
NC(=O)NO
InChI key
VSNHCAURESNICA-UHFFFAOYSA-N
InChI
1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
grade
pharmaceutical primary standard
API family
hydroxycarbamide
form
solid
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
BP
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
storage temp.
2-8°C
Gene Information
human ... RRM1(6240), RRM2(6241), RRM2B(50484)
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Biochem/physiol Actions
抗肿瘤剂。通过形成自由基硝基氧灭活核糖核苷还原酶，自由基硝基氧可结合到酶活性位点的酪氨酰自由基。这可阻断脱氧核苷酸的合成，从而抑制 DNA 合成，并且诱导细胞周期同步化或 S-期细胞死亡。
Application
Hydroxycarbamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
Also used in monographs such as:Hydroxycarbamide Capsules
Also used in monographs such as:
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).
Packaging
Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
signalword
Danger
hcodes
Hazard Classifications
Muta. 1B - Repr. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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