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经验公式(希尔记法):
C9H11F2N3O4 · HCl
化学文摘社编号:
分子量:
299.66
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1
SMILES string
Cl.NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)C2(F)F
InChI key
OKKDEIYWILRZIA-OSZBKLCCSA-N
grade
pharmaceutical primary standard
API family
gemcitabine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Gene Information
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General description
Application
本品为美国药典参考标准品(USP Reference Standard),用于专门的质量试验和分析。
也用于制备LC-UV法检测和杂质分析用标准溶液,用于下列美国药典(USP)专论中的药物分析:
也用于制备LC-UV法检测和杂质分析用标准溶液,用于下列美国药典(USP)专论中的药物分析:
- 盐酸吉西他滨
- 注射用吉西他滨
Biochem/physiol Actions
吉西他滨是一种广泛使用的抗肿瘤药和抗代谢药。
吉西他滨是诊所和研究实验室中广泛使用的抗肿瘤药物。它是一种抗肿瘤药和抗代谢药。
Analysis Note
这些产品仅供测试和化验使用。它们不适用于人类或动物,也不能用于诊断、治疗或治愈任何类型的疾病。
Other Notes
可能适用相应的销售限制。
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Gemcitabine for Injection
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 38(5), 2094-2094 (2021)
Gemcitabine Hydrochloride
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(4), 2093-2093 (2021)
Minggen Hu et al.
Surgical endoscopy, 28(9), 2584-2591 (2014-04-08)
Laparoscopic distal splenopancreatectomy (DSP) is an effective and safe surgical modality for treating benign and borderline distal pancreatic tumors, but rarely for pancreatic cancer. This study aimed to examine the feasibility, effectiveness, and safety of laparoscopic versus laparotomic DSP in
Jeffrey R Infante et al.
Investigational new drugs, 33(2), 432-439 (2015-02-03)
Background This Phase 1b study aimed to determine the recommended Phase 2 dose of LY2334737, an oral pro-drug of gemcitabine, in combination with capecitabine, an oral pro-drug of 5-fluorouracil, in patients with advanced solid tumors. In addition, pharmacokinetics (PK) and
Erez Hasnis et al.
Neoplasia (New York, N.Y.), 16(6), 501-510 (2014-06-25)
Weekly gemcitabine therapy is the major treatment offered for patients with pancreatic adenocarcinoma cancer; however, relative resistance of tumor cells to chemotherapy, rapid regrowth, and metastasis are the main causes of death within a year. Recently, the daily continuous administration
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