Merck
CN

COL4A4

collagen, type IV, alpha 4

Synonyms:
CA44
Species:
UniProtKB ID:
Gene ID:
  • Human(1286) Summary: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR. [provided by RefSeq, Jul 2008]
  • Mouse(12829) collagen, type IV, alpha 4
  • Rat(301562) collagen, type IV, alpha 4
  • naked mole-rat(101709839) collagen, type IV, alpha 4
  • Horse(100062160) collagen, type IV, alpha 4
  • dog(403841) collagen, type IV, alpha 4
  • domestic guinea pig(100732595) collagen, type IV, alpha 4
  • sheep(101118172) collagen, type IV, alpha 4
  • Zebrafish(554270) collagen, type IV, alpha 4
  • cow(407107) collagen, type IV, alpha 4
  • domestic cat(101091469) collagen, type IV, alpha 4
  • chicken(424799) collagen, type IV, alpha 4

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Collagen IV α4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry
Monoclonal Anti-Collagen, Type IV antibody produced in mouse, clone COL-94, ascites fluid,
Species Reactivity
human
Application
ELISA
dot blot

immunohistochemistry

microarray

Proteins

Product Number
Description
Species
Collagen from human placenta, Bornstein and Traub Type I (Sigma Type VIII), powder,
Species
human, cow
Collagen from human placenta, Bornstein and Traub Type IV, powder,
Species
human
Collagen from human placenta, Bornstein and Traub Type IV, powder,
Species
human
Collagen from human placenta, Bornstein and Traub Type IV, solution, suitable for cell culture, High Performance,
Species
human
Collagen from human placenta, Bornstein and Traub Type IV, powder, BioReagent, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Col4a4,
Species
mouse