Merck
CN

HDAC6

histone deacetylase 6

别名:
HD6
物种:
Human HDAC6 (10013), Mouse Hdac6 (15185), Rat Hdac6 (84581), sheep HDAC6 (101109245), Zebrafish hdac6 (565482), domestic guinea pig Hdac6 (100717988), dog HDAC6 (480907), fruit fly HDAC6 (32461), naked mole-rat Hdac6 (101708442), domestic cat HDAC6 (101084086)
UniProtKB ID:
Q9UBN7, O94975, Q6NT75, Q7L3E5, Q96CY0
基因ID:
  • Human(10013) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
  • Mouse(15185) histone deacetylase 6
  • Rat(84581) histone deacetylase 6
  • sheep(101109245) histone deacetylase 6
  • Zebrafish(565482) histone deacetylase 6
  • domestic guinea pig(100717988) histone deacetylase 6
  • dog(480907) histone deacetylase 6
  • fruit fly(32461) CG6170 gene product from transcript CG6170-RA
  • naked mole-rat(101708442) histone deacetylase 6
  • domestic cat(101084086) histone deacetylase 6
  • cow(513602) histone deacetylase 6

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Antibodies

货号
说明
物种反应性
应用
HPA026321
Anti-HDAC6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
WH0010013M1
Monoclonal Anti-HDAC6 antibody produced in mouse, clone 1E2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
AV31451
Anti-HDAC6 antibody produced in rabbit, affinity isolated antibody,
物种反应性
dog, horse, human, pig, rabbit
应用
ChIP
immunohistochemistry
western blot
HPA003714
Anti-HDAC6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
物种反应性
human
应用
immunohistochemistry
SAB4500011
Anti-HDAC6 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
SML0061
SAHA, ≥98% (HPLC),
物种
human
SML1175
罗咪酯肽, ≥98% (HPLC),
物种
human
C0621
CI−994, ≥98% (HPLC), powder,
物种
human

Proteins

货号
说明
物种
SRP0108
HDAC-6 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
物种
human
SRP0310
HDAC6 H216A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE),
物种
human
SRP0311
HDAC6 H611A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥79% (SDS-PAGE),
物种
human

esiRNA

货号
说明
物种
EMU055151
MISSION® esiRNA, targeting mouse Hdac6,
物种
mouse
EHU054851
MISSION® esiRNA, targeting human HDAC6,
物种
human