Merck
CN

KCNB1

potassium voltage-gated channel, Shab-related subfamily, member 1

Synonyms:
DRK1, KV2.1, h-DRK1
Species:
UniProtKB ID:
Gene ID:
  • Human(3745) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]
  • Mouse(16500) potassium voltage gated channel, Shab-related subfamily, member 1
  • Rat(25736) potassium voltage gated channel, Shab-related subfamily, member 1
  • naked mole-rat(101703076) potassium voltage-gated channel, Shab-related subfamily, member 1
  • cow(539528) potassium voltage-gated channel, Shab-related subfamily, member 1
  • chicken(428146) potassium voltage-gated channel, Shab-related subfamily, member 1
  • Zebrafish(555284) potassium voltage-gated channel, Shab-related subfamily, member 1
  • dog(485918) potassium voltage-gated channel, Shab-related subfamily, member 1
  • Horse(100057009) potassium voltage-gated channel, Shab-related subfamily, member 1
  • domestic cat(101101556) potassium voltage-gated channel, Shab-related subfamily, member 1
  • sheep(780775) potassium voltage-gated channel, Shab-related subfamily, member 1
  • Domestic Rabbit(100008779) potassium voltage-gated channel, Shab-related subfamily, member 1
  • sheep(101121535) potassium voltage-gated channel, Shab-related subfamily, member 1
  • domestic guinea pig(100725645) potassium voltage-gated channel, Shab-related subfamily, member 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KCNB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-KCNB1 antibody produced in mouse, clone S89-34, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-KCNB1 antibody produced in mouse, clone S4-11, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, monkey, mouse, rat
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-KCNB1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-KV2.1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Species
human
Guanidine hydrochloride solution, BioUltra, ~8 M in H2O,
Species
human
Guanidine hydrochloride, ≥98%,
Species
human
Guanidine hydrochloride, ≥99% (titration), organic base and chaeotropic agent,
Species
human
Guanidine hydrochloride, for molecular biology, ≥99%,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
2,3-Butanedione monoxime, ≥98%,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Kcnb1,
Species
mouse
MISSION® esiRNA, targeting human KCNB1,
Species
human