LOXL4
lysyl oxidase-like 4
Synonyms:
LOXC
Species:
Human LOXL4 (84171), Mouse Loxl4 (67573), Rat Loxl4 (309380), cow LOXL4 (281904), dog LOXL4 (486830), domestic cat LOXL4 (101083112), Horse LOXL4 (100070637), chicken LOXL4 (769927), Zebrafish loxl4 (100320658), domestic guinea pig Loxl4 (100722686) ...More
UniProtKB ID:
Gene ID:
- Human(84171) Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
- Mouse(67573) lysyl oxidase-like 4
- Rat(309380) lysyl oxidase-like 4
- cow(281904) lysyl oxidase-like 4
- dog(486830) lysyl oxidase-like 4
- domestic cat(101083112) lysyl oxidase-like 4
- Horse(100070637) lysyl oxidase-like 4
- chicken(769927) lysyl oxidase-like 4
- Zebrafish(100320658) lysyl oxidase-like 4
- domestic guinea pig(100722686) lysyl oxidase-like 4
- sheep(101117380) lysyl oxidase-like 4
- naked mole-rat(101707770) lysyl oxidase-like 4
- Domestic Rabbit(100357674) lysyl oxidase-like 4
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