OSCAR
osteoclast associated, immunoglobulin-like receptor
别名:
PIGR3, PIgR-3
物种:
Human OSCAR (126014), Mouse Oscar (232790), Rat Oscar (292537), cow OSCAR (100336423), dog OSCAR (484313)
UniProtKB ID:
基因ID:
- Human(126014) Summary: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(232790) osteoclast associated receptor
- Rat(292537) osteoclast associated, immunoglobulin-like receptor
- cow(100336423) osteoclast associated, immunoglobulin-like receptor
- dog(484313) osteoclast associated, immunoglobulin-like receptor
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Antibodies
Product Number
说明
物种反应性
应用
Anti-OSCAR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence