CN
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
Synonyms:
CD140A, PDGFR-2, PDGFR2, RHEPDGFRA
Species:
Human PDGFRA (5156), Mouse Pdgfra (18595), Rat Pdgfra (25267), chicken PDGFRA (395509), domestic guinea pig Pdgfra (100726209), cow PDGFRA (282301), Zebrafish pdgfra (386856), domestic cat PDGFRA (101090765), sheep PDGFRA (101106012), dog PDGFRA (442860) ...More
UniProtKB ID:
Gene ID:
- Human(5156) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
- Mouse(18595) platelet derived growth factor receptor, alpha polypeptide
- Rat(25267) platelet derived growth factor receptor, alpha polypeptide
- chicken(395509) platelet-derived growth factor receptor, alpha polypeptide
- domestic guinea pig(100726209) platelet-derived growth factor receptor, alpha polypeptide
- cow(282301) platelet-derived growth factor receptor, alpha polypeptide
- Zebrafish(386856) platelet derived growth factor receptor alpha
- domestic cat(101090765) platelet-derived growth factor receptor, alpha polypeptide
- sheep(101106012) platelet-derived growth factor receptor, alpha polypeptide
- dog(442860) platelet-derived growth factor receptor, alpha polypeptide
- Horse(100059815) platelet-derived growth factor receptor, alpha polypeptide
- naked mole-rat(101697360) platelet-derived growth factor receptor, alpha polypeptide
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Custom Gene Products
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ELISA
Product Number
Description
Species
Phosphotyrosine PDGFRA / Platelet-derived Growth Factor Receptor Alpha ELISA Kit, ,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-PDGFRα (Tyr754) Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
western blot
Anti-PDGFRα Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Anti-PDGFRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-CD140a antibody produced in mouse, clone 16A1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD140a-APC antibody produced in mouse, clone 16A1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PDGFR-α, active, GST tagged from mouse, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
mouse
PDGFR-α (D842V), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
PDGFRα Protein, active, 50 µg, Active, recombinant human PDGFRα, residues 550-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Species
human
PDGFR-α (T674I), active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human