Merck
CN

PRDM16

PR domain containing 16

别名:
CMD1LL, LVNC8, MEL1, PFM13
物种:
Human PRDM16 (63976), Mouse Prdm16 (70673), Rat Prdm16 (100366024), dog PRDM16 (479582), domestic cat PRDM16 (101090880), sheep PRDM16 (101120004), cow PRDM16 (100137803), Horse PRDM16 (100060844), Zebrafish prdm16 (559174), domestic guinea pig Prdm16 (100714489) ...展开
UniProtKB ID:
Q9HAZ2, A6NHQ8, B1AJP7, B1AJP8, B1AJP9, B1WB48, Q8WYJ9, Q9C0I8
基因ID:
  • Human(63976) Summary: The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(70673) PR domain containing 16
  • Rat(100366024) PR domain containing 16
  • dog(479582) PR domain containing 16
  • domestic cat(101090880) PR domain containing 16
  • sheep(101120004) PR domain containing 16
  • cow(100137803) PR domain containing 16
  • Horse(100060844) PR domain containing 16
  • Zebrafish(559174) PR domain containing 16
  • domestic guinea pig(100714489) PR domain containing 16
  • naked mole-rat(101721685) PR domain containing 16
  • chicken(419388) PR domain containing 16

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
ABE543
Anti-PRDM16 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
bovine, canine, guinea pig, horse, human, nonhuman primates
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA060467
Anti-PRDM16 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
SAB2900806
Anti-PRDM16 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
SAB1300006
抗-PRDM16（N-端） 兔抗, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry
HPA050343
Anti-PRDM16 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence