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Merck
CN

56485

Sigma-Aldrich

N-羟基硫代琥珀酰亚胺 钠盐

≥98% (HPLC), for peptide synthesis

别名:

磺基-NHS, 羟基-2,5-二氧代吡咯烷-3-磺酸 钠盐

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关于此项目

经验公式（希尔记法）:
C4H4NNaO6S
化学文摘社编号:
106627-54-7
分子量:
217.13
Beilstein:
6359129
MDL编号:
MFCD00043100
UNSPSC代码:
12352005
PubChem化学物质编号:
57651582
NACRES:
NA.22

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产品名称

N-羟基硫代琥珀酰亚胺 钠盐, ≥98% (HPLC)

质量水平

200

方案

≥98% (HPLC)

表单

powder

组成

carbon, 20.90-22.68 (anhydrous)
nitrogen, 6.10-6.61 (anhydrous)

反应适用性

reaction type: Addition Reactions

杂质

≤4% water

应用

peptide synthesis

官能团

imide
sulfonic acid

SMILES字符串

[Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O

InChI

1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1

InChI key

RPENMORRBUTCPR-UHFFFAOYSA-M

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相关类别

应用

N-羟基磺基琥珀酰亚胺钠盐是N-羟基琥珀酰亚胺的一种水溶性磺化类似物。它可以在碳二亚胺如1-乙基-3-（3-二甲基氨基丙基）碳二亚胺（EDC）存在时与羧酸发生偶联反应，形成亲水性的N-羟基磺基琥珀酰亚胺活性酯。这些酯可用于蛋白的交联实验。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

磺基-NHS可用于制备亲水性活性酯，如用于交联剂

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM7829
WXBF5621V
WXBF5173V
BCCM3588
BCCL3044

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N-hydroxysulfosuccinimide active esters: bis (N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers.
Staros JV
Biochemistry, 21(17), 3950-3955 (1982)
R Maydelid Trujillo-Nolasco et al.
Materials science & engineering. C, Materials for biological applications, 103, 109766-109766 (2019-07-28)
Radiosynovectomy is a technique used to decrease inflammation of the synovial tissue by intraarticular injection of a β-emitting radionuclide, such as 177Lu, which is suitable for radiotherapy due to its decay characteristics. Drug-encapsulating nanoparticles based on poly lactic‑co‑glycolic acid (PLGA)
Karen S Cheung Tung Shing et al.
Scientific reports, 8(1), 12457-12457 (2018-08-22)
A direct interaction between the erythropoietin (EPOR) and the beta-common (βc) receptors to form an Innate Repair Receptor (IRR) is controversial. On one hand, studies have shown a functional link between EPOR and βc receptor in tissue protection while others
P S Anjaneyulu et al.
International journal of peptide and protein research, 30(1), 117-124 (1987-07-01)
N-Hydroxysulfosuccinimide esters are reactive functional groups employed in a variety of protein modification reagents, especially cross-linking reagents. For these compounds, hydrolysis is the most important reaction competing for reaction of the esters with nucleophilic groups in proteins. We have employed
Eloy Povedano et al.
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This paper describes two different electrochemical affinity biosensing approaches for the simple, fast and bisulfite and PCR-free quantification of 5-methylated cytosines (5-mC) in DNA using the anti-5-mC antibody as biorecognition element. One of the biosensing approaches used the anti-5-mC as
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