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Sigma-Aldrich

ProClin 300

pkg of 400 mL, ProClin preservative for use in IVD manufacturing, CMIT/MIT 3 %

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Synonym(s):
3% solution of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one
NACRES:
NA.21

form

liquid

shelf life

3 yr

contains

Alkyl Carboxylate as stabilizer

composition

CMIT/MIT, 3%

packaging

pkg of 400 mL

parameter

<45 °C operating temperature

color

colorless to light yellow

matrix

Modified glycol

operating pH range

2.5-8.5

pH

4.1 (100 g/L)

bp

189 °C

mp

-40 °C

solubility

water: soluble

density

1.03 g/cm3

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Application

ProClin biocides are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin toxicity prevent microorganisms from developing high levels of resistance, making ProClin highly efficient even over extended storage periods of your IVD components.

Legal Information

ProClin is a trademark of LANXESS Corp.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

244.4 °F - closed cup

Flash Point(C)

118 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the concentration of active ingredients in ProClin 300?

    ProClin 300 contains a total of 3% active ingredient.  

  4. What is the matrix of the ProClin 300?

    ProClin 300 is a viscous solution containing 93-95 % Modified glycol and 2-3 % Alkyl carboxylate.

  5. When would I choose to use ProClin 300?

    ProClin 300 is best used with production runs of standards, controls, and large volume buffers and solutions.  The product is quite viscous and difficult to work with when trying to measure small volumes.

  6. What are the active ingredients in ProClin 300?

    ProClin 300 contains two active ingredients: 5-Chloro-2-methyl-4-isothiazolin-3-one (CMIT, CAS registry number 26172-55-4) and 2-Methyl-4-isothiazolin-3-one (MIT, CAS registry number 2682-20-4).  

  7. What is the density of ProClin 300?

    The density of ProClin 300 is reported as 8.59 pounds per gallon.  The Specific Gravity at 22°C is reported as 1.3 g/mL

  8. What is the weight of the 400 mL bottle of ProClin 300 weigh?

    The 400mL bottle of ProClin 300, including the contents, weighs approximately 500 grams.

  9. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  10. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  11. What is the density of ProClin 300?

    The density of ProClin 300 is reported as 8.59 pounds per gallon. The specific gravity at 22°C is reported as 1.03 g/mL.

  12. My question is not addressed here, how can I contact Technical Service for assistance?

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