Reliable TFF with Pellicon® Cassettes
Produced in Europe for supply resilience
Pellicon® 3 Cassettes Capacity Expansion
We are expanding our presence in Europe, the Middle East, and Africa with additional manufacturing capacity. By establishing in-region production for Pellicon® 3 cassettes in Blarney, Ireland, we are strengthening our supply chain resilience with shorter shipping distances. All supported by best-in-class global quality standards.
Pellicon® 3 cassettes deliver high product yield and consistent product purity and quality while offering broad chemical compatibility at every scale. They are available with Ultracel® and Biomax® membranes to meet various processing needs, including mAbs, viral vector therapies, vaccines, and more…
Experience the benefits of Pellicon® 3 cassettes for yourself—click here to request your free sample.
Why Pellicon® Cassettes?
- Proven Scalability – Consistent performance across cassette sizes supports seamless scale-up and scale-down from lab to full-scale manufacturing.
- High Product Recovery – Composite membrane design and optimized flow path maximize yield, even at high concentrations.
- Built for Demanding Conditions – Engineered to withstand high pressures, temperatures, and caustic cleaning—ideal for modern, high-titer processes.
- Void-Free Construction – Minimizes holdup volume and dead zones, improving process efficiency and reducing product loss.
- Easy to Use – Streamlined design enables fast installation, handling, and cleaning, reducing downtime and operator burden.
- Broad Chemical Compatibility – Designed to support a wide range of molecules and processes, including mAbs, vaccines, viral vectors, mRNA, pDNA, and more.
Specialized Membranes for Your Molecules
- Ultracel® Membrane – designed for the filtration of therapeutic proteins (such as monoclonal antibodies) and recombinant and non-recombinant proteins.
- Biomax® Membrane – perfect for the filtration of monoclonal antibodies and solutions containing albumin, hormones, vaccines and growth factors.
A versatile range of applications and benefits, including:
- Solvent clearance (DMAc and DMSO) by diafiltration in ADC manufacturing: Pellicon® Cassettes offer organic solvent compatibility with efficient clearance.
- Use of single-pass TFF with Pellicon® cassettes is an effective and streamlined strategy to tackle volume challenges within downstream processing.
- High viscosity products: Pellicon® 3 Cassettes with Ultracel® and Biomax® 30 kD Membrane utilizing D screen geometry are engineered to efficiently process higher viscosity products.
Backed by the Emprove® Program
Pellicon® 3 cassettes are supported by the Emprove® Program, which offers:
- Comprehensive documentation including product-specific quality data
- Support for qualification, risk assessment, and process optimization
- Data in easily accessible, ready-to-use dossiers
Streamline your workflow and boost productivity. Try Pellicon® Cassettes today!
Related Products
Related Resources
- Article: Tangential Flow Filtration in the Antibody Drug Conjugate (ADC) Manufacturing Process
Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.
- Tangential Flow Filtration in Downstream Bioprocessing
This article explains the different types of TFF, including single-use and multi-use, single pass TFF and batch TFF.
- White Paper: Streamlining Bioprocessing Using Pellicon® Cassettes for Single-pass Operation
Single-pass TFF is an enhanced approach to the existing TFF technology that has been used for the purification of monoclonal antibodies, therapeutic proteins, and vaccines at different steps within downstream processing.
- Application Note: Pellicon® 3 Cassettes with High Viscosity Feed Screen
Pellicon® 3 Cassettes with Ultracel® and Biomax® 30 kD Membrane utilizing D screen geometry are engineered to efficiently process higher viscosity products.
Get to Know the Products from Blarney
Experience the benefits of our filters for yourself. Request a free sample now by filling out the form below. Samples will be shipped from another factory until production in Blarney starts.
Blarney Products Trial Offer Official Rules. VALID ONLY in Austria, Belgium, Bulgaria, Croatia, Republic of Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland and the UK.
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