From single-use to multi-use, our tangential flow filtration (TFF) products are ideal for pharma and biopharma manufacturing.
Single-pass TFF with our Pellicon® capsules and cassettes streamlines processing by concentrating process streams without the recirculation of traditional TFF. This is a simple way to increase capacity, concentration, and product recovery while improving footprint. This versatile application also enables continuous and intensified processing, in which in-line volume reduction is coupled to other process steps.
Pellicon® Capsules with Ultracel® membrane are designed for streamlined ultrafiltration and diafiltration of biopharmaceuticals, offering ease of use and process flexibility. This innovative capsule is a true single-use TFF device with a unique plug-and-play, holderless design that comes ready to process in minutes.
Pellicon® 3 cassettes deliver high protein yield and consistent performance while offering broad chemical compatibility. They are available with Ultracel® and Biomax® membranes for different processing needs, including mAbs, plasma, insulin, peptides, and vaccines. To overcome high viscosity challenges, our Pellicon® 3 cassettes with D screen are optimized to achieve higher protein concentrations.
Pellicon® 2 cassettes are ideal for the ultrafiltration and diafiltration of biologics including concentration, desalting, and buffer exchange of polysaccharides, virus suspensions, and protein solutions. Our Ultracel® and Biomax® membranes offer efficient ultrafiltration while Durapore® membrane is best suited for microfiltration.
Pellicon® XL 50 cassettes couple our ultrafiltration and microfiltration membranes with linear scalability for process development or small-volume processing.
Prostak™ microfiltration modules provide robust construction, reliable performance, and steam-in-place capability, making them suitable for clarification, cell harvest, and multi-use perfusion. The low hold-up volume and open channel design allow high product recovery and gentle flow path for processing shear-sensitive materials.
Complementing our product portfolio, the Emprove® Program provides three types of dossiers to support different stages of development and manufacturing operations such as qualification, risk assessment, and process optimization. The dossiers consolidate comprehensive product-specific testing data, quality statements, and regulatory information in a readily available format to simplify your compliance needs.
There are many options for tangential flow filtration (TFF) in downstream bioprocessing from multi-use to single-use TFF or batch TFF and single-pass TFF.
Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.
Get practical guidance on using single-pass tangential flow filtration in your downstream process and scaling between capsules and cassettes.
Accelerate your therapy using our innovative single-use tangential flow filters with superior flux performance
The optimum tangential flow filtration devices for monoclonal antibodies and other therapeutic proteins.
The device of choice for applications requiring higher yield, fast processing, and exceptional chemical resistance
High performance tangential flow filters for biopharmaceutical process development, scale-up and scale-down, concentration, purification, and cell harvesting applications.
Prostak™ modules are tangential flow stacked plate membrane devices with open feed channels, made for use in Prostak™ tangential flow filtration (TFF) systems.
Easy-to-use, high performance, linearly scalable tangential flow filtration cassette for process development work at volumes from 50 to 1000 mL
Pellicon® single-pass tangential flow filtration (single-pass TFF) is a versatile technology for more productive, high capacity and cost effective downstream processes that allows facilities to meet the demands of higher titer and connected or continuous processes
The membrane of choice for ultra-low protein binding and robust performance during concentration and diafiltration of therapeutics
The membrane of choice for fast processing and exceptional chemical resistance
Innovative, high performance single-use tangential flow filtration devices that offer ease-of-use, operational flexibility, and enhanced operator safety.
The Pellicon® Capsule is the first of its kind—a true single-use TFF device that streamlines bioprocessing with its innovative, simplified design and user-friendly features.
The tangential flow filtration devices of choice for demanding filtration processes requiring unbeatable performance consistency.
The tangential flow filtration device of choice for demanding filtration processes requiring unbeatable performance consistency
Pellicon® 3 Cassettes with Ultracel® and Biomax® 30kD Membrane utilizing D screen geometry are engineered to efficiently process higher viscosity products.
Single-pass tangential flow filtration (SPTFF) is a method of ultrafiltration for the purposes of either volume reduction or protein concentration.
Single-pass TFF is an enhanced approach to the existing TFF technology that has been used for the purification of monoclonal antibodies, therapeutic proteins, and vaccines at different steps within downstream processing
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