SOD1
superoxide dismutase 1, soluble
Synonyms:
ALS, ALS1, IPOA, SOD, hSod1, homodimer
Species:
Human SOD1 (6647), Mouse Sod1 (20655), Rat Sod1 (24786), Domestic Rabbit SOD1 (100009313), dog SOD1 (403559), cow SOD1 (281495), Horse SOD1 (100033855), sheep SOD1 (101115136), domestic cat SOD1 (101091804), sheep SOD1 (100270717) ...More
UniProtKB ID:
Gene ID:
- Human(6647) Summary: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
- Mouse(20655) superoxide dismutase 1, soluble
- Rat(24786) superoxide dismutase 1, soluble
- Domestic Rabbit(100009313) superoxide dismutase 1, soluble
- dog(403559) superoxide dismutase 1, soluble
- cow(281495) superoxide dismutase 1, soluble
- Horse(100033855) superoxide dismutase 1, soluble
- sheep(101115136) superoxide dismutase 1, soluble
- domestic cat(101091804) superoxide dismutase 1, soluble
- sheep(100270717) superoxide dismutase 1, soluble
- chicken(395938) superoxide dismutase 1, soluble
- domestic guinea pig(100135622) superoxide dismutase 1, soluble
- Zebrafish(30553) superoxide dismutase 1, soluble
- naked mole-rat(101713304) superoxide dismutase 1, soluble
- Goat(100861196) superoxide dismutase 1, soluble
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