SOD1

superoxide dismutase 1, soluble

Synonyms:

ALS, ALS1, IPOA, SOD, hSod1, homodimer

Species:

UniProtKB ID:

Gene ID:

Human(6647) Summary: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
Mouse(20655) superoxide dismutase 1, soluble
Rat(24786) superoxide dismutase 1, soluble
Domestic Rabbit(100009313) superoxide dismutase 1, soluble
dog(403559) superoxide dismutase 1, soluble
cow(281495) superoxide dismutase 1, soluble
Horse(100033855) superoxide dismutase 1, soluble
sheep(101115136) superoxide dismutase 1, soluble
domestic cat(101091804) superoxide dismutase 1, soluble
sheep(100270717) superoxide dismutase 1, soluble
chicken(395938) superoxide dismutase 1, soluble
domestic guinea pig(100135622) superoxide dismutase 1, soluble
Zebrafish(30553) superoxide dismutase 1, soluble
naked mole-rat(101713304) superoxide dismutase 1, soluble
Goat(100861196) superoxide dismutase 1, soluble

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