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TNFAIP3

tumor necrosis factor, alpha-induced protein 3

Synonyms:
A20, OTUD7C, TNFA1P2
Species:
UniProtKB ID:
Gene ID:
  • Human(7128) Summary: This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]
  • Mouse(21929) tumor necrosis factor, alpha-induced protein 3
  • Rat(683206) tumor necrosis factor, alpha-induced protein 3
  • domestic guinea pig(100720503) tumor necrosis factor, alpha-induced protein 3
  • chicken(421684) tumor necrosis factor, alpha-induced protein 3
  • Zebrafish(564497) tumor necrosis factor, alpha-induced protein 3
  • dog(484006) tumor necrosis factor, alpha-induced protein 3
  • cow(508105) tumor necrosis factor, alpha-induced protein 3
  • Horse(100073197) tumor necrosis factor, alpha-induced protein 3
  • domestic cat(101083682) tumor necrosis factor, alpha-induced protein 3
  • sheep(101113156) tumor necrosis factor, alpha-induced protein 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-mA20 Antibody/TNFAIP3, clone 37, clone 37, 0.5 mg/mL, from rat,
Species Reactivity
mouse
Application
flow cytometry
Anti-TNFAIP3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-TNFAIP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-A20 Mouse mAb (59A426), liquid, clone 59A426, Calbiochem®,
Species Reactivity
human
Application
Anti-TNFAIP3 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution, ab1,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
A20 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥20% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Tnfaip3,
Species
mouse
MISSION® esiRNA, targeting human TNFAIP3,
Species
human