Skip to Content
Merck
CN

108413

Methyl chloroacetate

99%

Synonym(s):

Chloroacetic acid methyl ester, Methyl 2-chloroacetate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
ClCH2COOCH3
CAS Number:
96-34-4
Molecular Weight:
108.52
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24846666
EC Number:
202-501-1
Beilstein/REAXYS Number:
506255
MDL number:
MFCD00000931
Assay:
99%

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

QABLOFMHHSOFRJ-UHFFFAOYSA-N

InChI

1S/C3H5ClO2/c1-6-3(5)2-4/h2H2,1H3

SMILES string

COC(=O)CCl

vapor density

3.8 (vs air)

vapor pressure

10 mmHg ( 25 °C), 5.25 mmHg ( 20 °C)

assay

99%

autoignition temp.

869 °F

expl. lim.

18.5 %

Quality Level

100

bp

130 °C/740 mmHg (lit.)

mp

−33 °C (lit.)

solubility

H2O: insoluble, alcohol: miscible, diethyl ether: miscible

density

1.238 g/mL at 25 °C (lit.)

functional group

chloro, ester

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Methyl chloroacetate acts as extraction solvent during the separation of neutral compounds with concentration enhancement using coupling liquid–liquid semimicroextraction with micellar electrokinetic chromatography through on-capillary decomposition. It regenerates the PdCl2-CuCl2/activated carbon catalyst used for synthesis of dimethyl carbonate.

Application

Methyl chloroacetate was used in the preparation of (carboxymethyl) trimethylammonium chloride esters. It may be used in the synthesis of octakis-(carbethoxymethoxy)calix[8]arene.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

116.6 °F - closed cup

flash_point_c

47 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SDBB3223
STBL3775
STBL3943
STBK5997
MKCR9778

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The effects of promoters on catalytic properties and deactivation-regeneration of the catalyst in the synthesis of dimethyl carbonate.
Ruixia J, et al.
Applied Catalysis A: General, 238(1), 131-139 (2003)
A W Lloyd et al.
The Journal of pharmacy and pharmacology, 46(9), 704-707 (1994-09-01)
Glycinebetaine and N-modified betaines have been previously shown to be effective at reducing leakage from liposomes on freeze-thaw procedures. This study involved the preparation of a series of other modified betaines and the comparison of their abilities to reduce leakage
Nonionogenic star-shaped calix [8] arenes: Synthesis and ionophore properties.
Ten'kovtsev AV and Razina AB.
Russian Journal of Applied Chemistry, 82(9), 1615-1619 (2009)
Tianlin Wang et al.
Journal of chromatography. A, 1147(1), 105-110 (2007-03-03)
This paper reports the use of methyl chloroacetate (MCA) as an extraction solvent for coupling liquid-liquid semimicroextraction (LLsME) with micellar electrokinetic chromatography (MEKC) through on-capillary decomposition for the separation of neutral compounds with concentration enhancement. Alkylphenones of C(8), C(10) and
Daniele Tedesco et al.
Chirality, 27(12), 914-918 (2015-10-09)
Caffeic acid-derived polyethers are a class of natural products isolated from the root extracts of comfrey and bugloss, which are endowed with intriguing pharmacological properties as anticancer agents. The synthesis of new polyether derivatives is achieved through ring-opening polymerization of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service