113727
Norphenylephrine hydrochloride
98%
Synonym(s):
α-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride, 3,α-Dihydroxyphenethylamine hydrochloride, Norfenefrine hydrochloride
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About This Item
Linear Formula:
HOC6H4CH(CH2NH2)OH · HCl
CAS Number:
Molecular Weight:
189.64
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
225-323-6
MDL number:
Assay:
98%
Form:
solid
InChI key
OWMFSWZUAWKDRR-UHFFFAOYSA-N
InChI
1S/C8H11NO2.ClH/c9-5-8(11)6-2-1-3-7(10)4-6;/h1-4,8,10-11H,5,9H2;1H
SMILES string
Cl.NCC(O)c1cccc(O)c1
assay
98%
form
solid
mp
162-164 °C (lit.)
functional group
amine, hydroxyl
Quality Level
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Application
Norphenylephrine hydrochloride was used in the study of the effects of phenylephrine on the isolated heart of rabbit.
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M Maeda et al.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 41(5), 463-469 (1990-01-01)
[11C]-p- and m-octopamine hydrochloride were synthesized from [11C]HCN in a two-step sequence. Chemical and enzymatic approaches were used for the formation of the [11C]cyanohydrin intermediates as the key step. Isolated radiochemical yields of 0.7-2.3% at the end-of-synthesis were obtained with
J C David et al.
Journal of neurochemistry, 53(1), 149-154 (1989-07-01)
Functions of octopamine in the mammalian brain are still not well known. An important aspect of this problem is the relationship between octopamines and catecholamines. Previous data have shown that their respective ontogenic evolutions are not parallel. Do the changes
O Oldenburg et al.
Deutsche medizinische Wochenschrift (1946), 124(1-2), 8-12 (1999-02-10)
A 71-year-old man was admitted because of treatment-resistant orthostatic hypotension of unknown aetiology. When aged 64 years he developed some impotence and later urinary incontinence and urinary frequency. At 68 years he noted vertigo on physical activity, and a year
L Jørgensen et al.
Urologia internationalis, 46(2), 176-179 (1991-01-01)
To study the acute effect of norfenefrine, given orally in aqueous solution, on the urethral closure function, profilometry was performed before and after administration of placebo and increasing doses of norfenefrine in 6 females with genuine stress incontinence. A weak
J F Coulon et al.
Journal of neurochemistry, 52(5), 1418-1424 (1989-05-01)
Phenolamines, particularly octopamines, are of special importance in avoidance behavior. In the Roman low avoidance (RLA) strain, p-octopamine can induce locomotor behavioral activity that is normally observed in the Roman high avoidance (RHA) strain. For these reasons, the levels of
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