113832
3,5-Diaminobenzoic acid dihydrochloride
99%
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About This Item
Linear Formula:
(H2N)2C6H3CO2H·2HCl
CAS Number:
Molecular Weight:
225.07
Beilstein:
3703362
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
Assay
99%
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
application(s)
peptide synthesis
SMILES string
Cl[H].Cl[H].Nc1cc(N)cc(c1)C(O)=O
InChI
1S/C7H8N2O2.2ClH/c8-5-1-4(7(10)11)2-6(9)3-5;;/h1-3H,8-9H2,(H,10,11);2*1H
InChI key
IGPLRBRBTUNCRT-UHFFFAOYSA-N
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Application
Uses include the fluorometric microdetermination of DNA.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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[Improved fluorometric method for DNA microanalysis].
M M Vilenchik et al.
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia, (2)(2), 217-222 (1984-03-01)
Céline Douat-Casassus et al.
Journal of the American Chemical Society, 126(25), 7817-7826 (2004-06-24)
Peptide dendrimers incorporating 3,5-diaminobenzoic acid 1 as a branching unit (B) were prepared by solid-phase synthesis of ((Ac-A(3))(2)B-A(2))(2)B-Cys-A(1)-NH(2) followed by disulfide bridge formation. Twenty-one homo- and heterodimeric dendrimers were obtained by permutations of aspartate, histidine, and serine at positions A(1)
Interference of Bis-Tris buffer with the diaminobenzoic acid fluorescence assay used to quantify DNA.
W E Schy et al.
Mutation research, 226(4), 263-266 (1989-08-01)
J Beckmann et al.
Acta diabetologica latina, 18(1), 51-57 (1981-01-01)
DNA content seems to be an ideal reference parameter for data on secretory function or metabolism of pancreatic islets. The approved fluorometric DNA assay with diaminobenzoic acid (DABA) of Kissane and Robins comprises repeated ethanol extractions of the tissue for
Wei-Yu Chen et al.
Analytical chemistry, 75(16), 4223-4228 (2003-11-25)
The alkali cation adductions of oligonucleotides dramatically degrade MALDI mass spectra and even affect the detection limit. Desalting is generally involved in MALDI sample preparation. This work demonstrates the feasibility of using 3,4-diaminobenzoic acid (DABA) and 3,5-DABA as the MALDI
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